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dc.contributor.authorCakan G.en_US
dc.contributor.authorBezirci F.B.en_US
dc.contributor.authorKacka, A.en_US
dc.contributor.authorCesur, S.en_US
dc.contributor.authorAksaray, S.en_US
dc.contributor.authorTezeren, D.en_US
dc.contributor.authorSaka, D.en_US
dc.contributor.authorAhmed, K.en_US
dc.date.accessioned2016-02-08T10:07:02Z
dc.date.available2016-02-08T10:07:02Z
dc.date.issued2008en_US
dc.identifier.issn13446304
dc.identifier.urihttp://hdl.handle.net/11693/22958
dc.description.abstractThis study was performed to evaluate commercial brucella immunoglobulin G and M-enzymelinked immunosorbent assay (IgG and IgM ELISA) kits for the diagnosis of human brucellosis and to suggest a candidate prognostic marker for human brucellosis. We determined the serum levels of brucella IgG, IgM, C-reactive protein (CRP), soluble CD14 (sCD 14), and neopterin in patients with brucellosis and compared them with those of normal healthy persons, patients with tuberculosis, and patients with other diseases. It was found that the sensitivity of ELISA to diagnose brucellosis was high when both IgG and IgM ELISA were used together. This study showed that serum CRP, sCD14, or neopterin levels were significantly high during the course of human brucellosis. The above markers, alone or in combination, might have the potential to evaluate treatment outcomes in human brucellosis. The markers that can predict the variability of agglutination titer was also determined. It was found that the titer value alone does not fully represent disease status.en_US
dc.language.isoEnglishen_US
dc.source.titleJapanese Journal of Infectious Diseasesen_US
dc.subjectC reactive proteinen_US
dc.subjectCD14 antigenen_US
dc.subjectimmunoglobulin Gen_US
dc.subjectimmunoglobulin Men_US
dc.subjectneopterinen_US
dc.subjectrose bengalen_US
dc.subjectbacterium antibodyen_US
dc.subjectimmunoglobulinen_US
dc.subjectadulten_US
dc.subjectagglutination testen_US
dc.subjectarticleen_US
dc.subjectblood samplingen_US
dc.subjectBrucellaen_US
dc.subjectbrucellosisen_US
dc.subjectcontrolled studyen_US
dc.subjectdiagnostic valueen_US
dc.subjectdisease courseen_US
dc.subjectdisease markeren_US
dc.subjectenzyme linked immunosorbent assayen_US
dc.subjectfemaleen_US
dc.subjecthumanen_US
dc.subjectmajor clinical studyen_US
dc.subjectmaleen_US
dc.subjectoutcome assessmenten_US
dc.subjectpredictionen_US
dc.subjectprognosisen_US
dc.subjectsensitivity and specificityen_US
dc.subjecttuberculosisen_US
dc.subjectadolescenten_US
dc.subjectanalytical equipmenten_US
dc.subjectblooden_US
dc.subjectevaluationen_US
dc.subjectimmunologyen_US
dc.subjectmicrobiologyen_US
dc.subjectmiddle ageden_US
dc.subjectAdolescenten_US
dc.subjectAdulten_US
dc.subjectAntibodies, Bacterialen_US
dc.subjectAntigens, CD14en_US
dc.subjectBrucellaen_US
dc.subjectBrucellosisen_US
dc.subjectC-Reactive Proteinen_US
dc.subjectEnzyme-Linked Immunosorbent Assayen_US
dc.subjectFemaleen_US
dc.subjectHumansen_US
dc.subjectImmunoproteinsen_US
dc.subjectMaleen_US
dc.subjectMiddle Ageden_US
dc.subjectNeopterinen_US
dc.subjectReagent Kits, Diagnosticen_US
dc.subjectSensitivity and Specificityen_US
dc.titleAssessment of diagnostic enzyme-linked immunosorbent assay kit and serological markers in human brucellosisen_US
dc.typeArticleen_US
dc.departmentDepartment of Molecular Biology and Geneticsen_US
dc.citation.spage366en_US
dc.citation.epage370en_US
dc.citation.volumeNumber61en_US
dc.citation.issueNumber5en_US


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