mESAdb: microRNA expression and sequence analysis database
Date
2011Source Title
Nucleic Acids Research
Print ISSN
0305-1048
Electronic ISSN
1362-4962
Publisher
Oxford University Press
Volume
39
Pages
D170 - D180
Language
English
Type
ArticleItem Usage Stats
171
views
views
170
downloads
downloads
Abstract
MicroRNA expression and sequence analysis database (http://konulab.fen. bilkent.edu.tr/mirna/) (mESAdb) is a regularly updated database for the multivariate analysis of sequences and expression of microRNAs from multiple taxa. mESAdb is modular and has a user interface implemented in PHP and JavaScript and coupled with statistical analysis and visualization packages written for the R language. The database primarily comprises mature microRNA sequences and their target data, along with selected human, mouse and zebrafish expression data sets. mESAdb analysis modules allow (i) mining of microRNA expression data sets for subsets of microRNAs selected manually or by motif; (ii) pair-wise multivariate analysis of expression data sets within and between taxa; and (iii) association of microRNA subsets with annotation databases, HUGE Navigator, KEGG and GO. The use of existing and customized R packages facilitates future addition of data sets and analysis tools. Furthermore, the ability to upload and analyze user-specified data sets makes mESAdb an interactive and expandable analysis tool for microRNA sequence and expression data.
Keywords
Computer interfaceGene expression
Gene function
Genetic association
Information processing
MicroRNA expression and sequence analysis database
Priority journal
RNA sequence
Sequence analysis
Sequence database
Statistical analysis
Animals
Databases
Humans
Mice
MicroRNAs
Software
Systems Integration
Danio rerio
Permalink
http://hdl.handle.net/11693/22055Published Version (Please cite this version)
http://dx.doi.org/10.1093/nar/gkq1256Collections
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