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dc.contributor.authorPrüfer, K.en_US
dc.contributor.authorMunch, K.en_US
dc.contributor.authorHellmann I.en_US
dc.contributor.authorAkagi, K.en_US
dc.contributor.authorMiller J.R.en_US
dc.contributor.authorWalenz, B.en_US
dc.contributor.authorKoren, S.en_US
dc.contributor.authorSutton G.en_US
dc.contributor.authorKodira, C.en_US
dc.contributor.authorWiner, R.en_US
dc.contributor.authorKnight J.R.en_US
dc.contributor.authorMullikin J.C.en_US
dc.contributor.authorMeader, S.J.en_US
dc.contributor.authorPonting, C.P.en_US
dc.contributor.authorLunter G.en_US
dc.contributor.authorHigashino, S.en_US
dc.contributor.authorHobolth, A.en_US
dc.contributor.authorDutheil J.en_US
dc.contributor.authorKarakoç, E.en_US
dc.contributor.authorAlkan, C.en_US
dc.contributor.authorSajjadian, S.en_US
dc.contributor.authorCatacchio, C.R.en_US
dc.contributor.authorVentura, M.en_US
dc.contributor.authorMarques-Bonet, T.en_US
dc.contributor.authorEichler, E.E.en_US
dc.contributor.authorAndré, C.en_US
dc.contributor.authorAtencia, R.en_US
dc.contributor.authorMugisha L.en_US
dc.contributor.authorJunhold J.en_US
dc.contributor.authorPatterson, N.en_US
dc.contributor.authorSiebauer, M.en_US
dc.contributor.authorGood J.M.en_US
dc.contributor.authorFischer, A.en_US
dc.contributor.authorPtak, S.E.en_US
dc.contributor.authorLachmann, M.en_US
dc.contributor.authorSymer, D.E.en_US
dc.contributor.authorMailund, T.en_US
dc.contributor.authorSchierup, M.H.en_US
dc.contributor.authorAndrés, A.M.en_US
dc.contributor.authorKelso J.en_US
dc.contributor.authorPääbo, S.en_US
dc.date.accessioned2016-02-08T09:46:06Z
dc.date.available2016-02-08T09:46:06Z
dc.date.issued2012en_US
dc.identifier.issn0028-0836
dc.identifier.urihttp://hdl.handle.net/11693/21424
dc.description.abstractTwo African apes are the closest living relatives of humans: the chimpanzee (Pan troglodytes) and the bonobo (Pan paniscus). Although they are similar in many respects, bonobos and chimpanzees differ strikingly in key social and sexual behaviours, and for some of these traits they show more similarity with humans than with each other. Here we report the sequencing and assembly of the bonobo genome to study its evolutionary relationship with the chimpanzee and human genomes. We find that more than three per cent of the human genome is more closely related to either the bonobo or the chimpanzee genome than these are to each other. These regions allow various aspects of the ancestry of the two ape species to be reconstructed. In addition, many of the regions that overlap genes may eventually help us understand the genetic basis of phenotypes that humans share with one of the two apes to the exclusion of the other. © 2012 Macmillan Publishers Limited. All rights reserved.en_US
dc.language.isoEnglishen_US
dc.source.titleNatureen_US
dc.relation.isversionofhttp://dx.doi.org/10.1038/nature11128en_US
dc.subjectancestryen_US
dc.subjectevolutionary biologyen_US
dc.subjectgenomeen_US
dc.subjectlife history traiten_US
dc.subjectphenotypeen_US
dc.subjectprimateen_US
dc.subjectsexual behavioren_US
dc.subjectalleleen_US
dc.subjectarticleen_US
dc.subjectchimpanzeeen_US
dc.subjectchromosome analysisen_US
dc.subjectcontrolled studyen_US
dc.subjectgene duplicationen_US
dc.subjectgene sequenceen_US
dc.subjectgenome analysisen_US
dc.subjectgeographic distributionen_US
dc.subjecthumanen_US
dc.subjecthuman genomeen_US
dc.subjectmolecular evolutionen_US
dc.subjectnonhumanen_US
dc.subjectPan paniscusen_US
dc.subjectphenotypeen_US
dc.subjectpriority journalen_US
dc.subjectspecies comparisonen_US
dc.subjecttransposonen_US
dc.subjectAnimalsen_US
dc.subjectDNA Transposable Elementsen_US
dc.subjectEvolution, Molecularen_US
dc.subjectGene Duplicationen_US
dc.subjectGenetic Variationen_US
dc.subjectGenomeen_US
dc.subjectGenome, Humanen_US
dc.subjectGenotypeen_US
dc.subjectHumansen_US
dc.subjectMolecular Sequence Dataen_US
dc.subjectPan paniscusen_US
dc.subjectPan troglodytesen_US
dc.subjectPhenotypeen_US
dc.subjectPhylogenyen_US
dc.subjectSpecies Specificityen_US
dc.subjectPanen_US
dc.subjectPan paniscusen_US
dc.subjectPan troglodytesen_US
dc.titleThe bonobo genome compared with the chimpanzee and human genomesen_US
dc.typeArticleen_US
dc.departmentDepartment of Computer Engineering
dc.citation.spage527en_US
dc.citation.epage531en_US
dc.citation.volumeNumber486en_US
dc.citation.issueNumber7404en_US
dc.identifier.doi10.1038/nature11128en_US


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