• About
  • Policies
  • What is openaccess
  • Library
  • Contact
Advanced search
      View Item 
      •   BUIR Home
      • Scholarly Publications
      • Institute of Materials Science and Nanotechnology (UNAM)
      • View Item
      •   BUIR Home
      • Scholarly Publications
      • Institute of Materials Science and Nanotechnology (UNAM)
      • View Item
      JavaScript is disabled for your browser. Some features of this site may not work without it.

      Antibacterial electrospun poly(lactic acid) (PLA) nanofibrous webs incorporating triclosan/cyclodextrin inclusion complexes

      Thumbnail
      View / Download
      1.4 Mb
      Author
      Kayaci F.
      Umu O.C.O.
      Tekinay, T.
      Uyar, T.
      Date
      2013
      Source Title
      Journal of Agricultural and Food Chemistry
      Print ISSN
      218561
      Volume
      61
      Issue
      16
      Pages
      3901 - 3908
      Language
      English
      Type
      Article
      Item Usage Stats
      149
      views
      1,277
      downloads
      Abstract
      Solid triclosan/cyclodextrin inclusion complexes (TR/CD-IC) were obtained and then incorporated in poly(lactic acid) (PLA) nanofibers via electrospinning. α-CD, β-CD, and γ-CD were tested for the formation of TR/CD-IC by a coprecipitation method; however, the findings indicated that α-CD could not form an inclusion complex with TR, whereas β-CD and γ-CD successfully formed TR/CD-IC crystals, and the molar ratio of TR to CD was found to be 1:1. The structural and thermal characteristics of TR/CD-IC were investigated by 1H NMR, FTIR, XRD, DSC, and TGA studies. Then, the encapsulation of TR/β-CD-IC and TR/γ-CD-IC in PLA nanofibers was achieved. Electrospun PLA and PLA/TR nanofibers obtained for comparison were uniform, whereas the aggregates of TR/CD-IC crystals were present and distributed within the PLA fiber matrix as confirmed by SEM and XRD analyses. The antibacterial activity of these nanofibrous webs was investigated. The results indicated that PLA nanofibers incorporating TR/CD-IC showed better antibacterial activity against Staphylococcus aureus and Escherichia coli bacteria compared to PLA nanofibers containing only TR without CD-IC. Electrospun nanofibrous webs incorporating TR/CD-IC may be applicable in active food packaging due to their very high surface area and nanoporous structure as well as efficient antibacterial property. © 2013 American Chemical Society.
      Keywords
      cyclodextrin
      electrospinning
      inclusion complex
      nanofiber
      poly(lactic acid) (PLA)
      triclosan
      Anti-bacterial activity
      Antibacterial properties
      Coprecipitation method
      Escherichia coli bacteria
      Inclusion complex
      Polylactic acids
      Thermal characteristics
      Triclosan
      Bacteria
      Cyclodextrins
      Electrospinning
      Lactic acid
      Nanofibers
      antiinfective agent
      cyclodextrin
      lactic acid
      nanofiber
      polylactic acid
      polymer
      triclosan
      article
      chemistry
      equipment
      food packaging
      methodology
      scanning electron microscopy
      Anti-Bacterial Agents
      Cyclodextrins
      Food Packaging
      Lactic Acid
      Microscopy, Electron, Scanning
      Nanofibers
      Polymers
      Triclosan
      Bacteria (microorganisms)
      Escherichia coli
      Staphylococcus aureus
      Permalink
      http://hdl.handle.net/11693/20999
      Published Version (Please cite this version)
      http://dx.doi.org/10.1021/jf400440b
      Collections
      • Institute of Materials Science and Nanotechnology (UNAM) 1775
      Show full item record

      Related items

      Showing items related by title, author, creator and subject.

      • Thumbnail

        Antioxidant α-tocopherol/γ-cyclodextrin–inclusion complex encapsulated poly(lactic acid) electrospun nanofibrous web for food packaging 

        Aytac, Z.; Keskin, N. O. S.; Tekinay, T.; Uyar, Tamer (John Wiley and Sons Inc., 2017-01)
        α-Tocopherol (α-TC) and α-TC/cyclodextrin (CD)–inclusion complex (IC) incorporated electrospun poly(lactic acid) (PLA) nanofibers (NF) were developed via electrospinning (PLA/α-TC–NF and PLA/α-TC/γ-CD–IC–NF). The release ...
      • Thumbnail

        Encapsulation of gallic acid/cyclodextrin inclusion complex in electrospun polylactic acid nanofibers: release behavior and antioxidant activity of gallic acid 

        Aytac Z.; Kusku S. I.; Durgun, Engin; Uyar, Tamer (Elsevier, 2016-06)
        Cyclodextrin-inclusion complexes (CD-ICs) possess great prominence in food and pharmaceutical industries due to their enhanced ability for stabilization of active compounds during processing, storage and usage. Here, CD-IC ...
      • Thumbnail

        Effect of double growth factor release on cartilage tissue engineering 

        Ertan, A.B.; Yilgor P.; Bayyurt, B.; Çalikoǧlu, A.C.; Kaspar Ç.; Kök F.N.; Kose G.T.; Hasirci V. (2013)
        The effects of double release of insulin-like growth factor I (IGF-I) and growth factor β1 (TGF-β1) from nanoparticles on the growth of bone marrow mesenchymal stem cells and their differentiation into cartilage cells were ...

      Browse

      All of BUIRCommunities & CollectionsTitlesAuthorsAdvisorsBy Issue DateKeywordsTypeDepartmentsThis CollectionTitlesAuthorsAdvisorsBy Issue DateKeywordsTypeDepartments

      My Account

      Login

      Statistics

      View Usage StatisticsView Google Analytics Statistics

      Bilkent University

      If you have trouble accessing this page and need to request an alternate format, contact the site administrator. Phone: (312) 290 1771
      Copyright © Bilkent University - Library IT

      Contact Us | Send Feedback | Off-Campus Access | Admin | Privacy