Show simple item record

dc.contributor.authorCetin, B.en_US
dc.contributor.authorAsik, M. D.en_US
dc.contributor.authorTaze, S.en_US
dc.date.accessioned2016-02-08T09:37:04Z
dc.date.available2016-02-08T09:37:04Z
dc.date.issued2013en_US
dc.identifier.issn1949-2944
dc.identifier.urihttp://hdl.handle.net/11693/20877
dc.description.abstractChitosan nanoparticles have a biodegradable, biocompatible, nontoxic structure, and are commonly used for drug delivery systems. In this study, design, modeling, and fabrication methodology of a microfluidic device for the synthesis of chitosan nanoparticles is presented. In the modeling, 2D flow and concentration field is computed using COMSOL Multiphysics® simulation environment to predict the performance of the device. The microfluidic chip is fabricated out of PDMS. The fabrication of the mold for the microfluidic device is performed using high-precision micromachining. Some preliminary proof-of-concept experiments were performed. It was observed that compared to conventional batch-type methods, the proposed microfluidic device can perform the synthesis much faster and in a much automated and convenient manner. Copyright © 2013 by ASME.en_US
dc.language.isoEnglishen_US
dc.source.titleJournal of Nanotechnology in Engineering and Medicineen_US
dc.relation.isversionofhttp://dx.doi.org/10.1115/1.4026287en_US
dc.titleDesign and fabrication of a microfluidic device for synthesis of chitosan nanoparticlesen_US
dc.typeArticleen_US
dc.departmentDepartment of Mechanical Engineeringen_US
dc.citation.volumeNumber4en_US
dc.citation.issueNumber3en_US
dc.identifier.doi10.1115/1.4026287en_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record