Cytotoxic and bioactive properties of different color tulip flowers and degradation kinetic of tulip flower anthocyanins
Author
Sagdic, O.
Ekici, L.
Ozturk, I.
Tekinay, T.
Polat, B.
Tastemur, B.
Bayram, O.
Senturk, B.
Date
2013Source Title
Food and Chemical Toxicology
Print ISSN
0278-6915
Publisher
Pergamon Press
Volume
58
Pages
432 - 439
Language
English
Type
ArticleItem Usage Stats
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Abstract
This study was conducted to determine the potential use of anthocyanin-based extracts (ABEs) of wasted tulip flowers as food/drug colorants. For this aim, wasted tulip flowers were samples and analyzed for their bioactive properties and cytotoxicity. Total phenolic contents of the extracts of the claret red (126.55. mg of gallic acid equivalent (GAE)/g dry extract) and orange-red (113.76. mg GAE/g dry extract) flowers were the higher than those of the other tulip flowers. Total anthocyanin levels of the violet, orange-red, claret red and pink tulip flower extracts were determined as 265.04, 236.49, 839.08 and 404.45. mg pelargonidin 3-glucoside/kg dry extract, respectively and these levels were higher than those of the other flowers. The extracts were more effective for the inhibition of Listeria monocytogenes, Staphylococcus aureus and Yersinia enterocolitica compared to other tested bacteria. Additionally, the cytotoxic effects of five different tulip flower extracts on human breast adenocarcinoma (MCF-7) cell line were investigated. The results showed that the orange red, pink and violet extracts had no cytotoxic activity against MCF-7 cell lines while yellow and claret red extracts appeared to be toxic for the cells. Overall, the extracts of tulip flowers with different colors possess remarkable bioactive and cytotoxic properties. © 2013 Elsevier Ltd.
Keywords
BioactivityCytotoxicity
Kinetic
Wasted tulip flowers
Alcohol
Anthocyanin
Antiinfective agent
Antioxidant
Phenol derivative
Plant extract
Tulipa gesneriana extract
Unclassified drug
Water
Antibacterial activity
Antioxidant activity
Bacterial growth
Biological activity
Cell strain MCF 7
Cell survival
Cell viability
Controlled study
Cytotoxicity
Cytotoxicity test
Degradation kinetics
Drug determination
Flower
Ggrowth inhibition
Human
Human cell
Listeria monocytogenes
Nonhuman
Staphylococcus aureus
Survival rate
Thermostability