Rational design and synthesis of bodipy dyes for molecular sensing, light harvesting and photodynamic applications
Author(s)
Advisor
Date
2014Publisher
Bilkent University
Language
English
Type
ThesisItem Usage Stats
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Abstract
BODIPY dyes have been addressed in many applications due to highly important
features. These unique properties can be summarized as high photostability, high
extinction coefficient, easy functionality, etc. Thus, tremendous studies have been
published and, ion sensing, photodynamic therapy, dye-sensitized solar cells and
light harvesting are some of the areas that BODIPY dyes have been utilized. In this
thesis, BODIPY dyes were functionalized to be used for different concepts. In the
first study, the main purpose was to seek for ion signaling differences of two
isomeric tetra-styryl BODIPY dyes with charge donor ligand located at 1,7 versus
3,5 positions. Second work focuses on the light harvesting concept with the use of
tetra-styryl BODIPY derivatives. Third study describes the coupling of energy
transfer with internal charge transfer to monitor the alterations in intensity ratios, so,
dynamic range of the fluorescent probe is improved. Design and synthesis of
BODIPY dyes for detection of biological thiols in aqueous solution both
chromogenically and fluorogenically was given in fourth study. Another biologically
important molecule, hydrogen sulfide is selectively detected via BODIPY-based
probe and depicted in the fifth study. In the sixth work, persistent luminescent
nanoparticles are attached to BODIPY-based photosensitizer to activate the
photodynamic action.
Keywords
ion sensingexcitation energy transfer
light harvesting
biological thiols
hydrogen sulfide
photodynamic therapy
BODIPY