The nature of post-Cold War decade Turkish-American relations has largely been determined by the new strategic circumstances that also have stared to frame world politics. In this decade, new challenges and opportunities brought together new areas of cooperation for the U.S. and Turkey by strengthening their alliance within NATO. Hence, the mutual importance attributed to the relationship has flourished as a result of the essentiality of their alliance. Neither the U.S. nor Turkey could afford to lose a significant ally with whom they share common interests in the region. Furthermore, it could be argued that these allies will need each other in the future to realize their foreign policy objectives concerning the relations with the neighboring countries. Thus, the simpler approach to the thesis is analyzing the exogenous and indigenous factors that affect the character of Turkish-American relations in the post-Cold War era.