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      • Theses - Graduate Program in Materials Science and Nanotechnology
      • Graduate Program in Materials Science and Nanotechnology - Ph.D. / Sc.D.
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      Design, synthesis and characterization of bioinspired nanomaterials for engineering and biomedicine

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      Author(s)
      Ceylan, Hakan
      Advisor
      Tekinay, Ayşe Begüm
      Date
      2014
      Publisher
      Bilkent University
      Language
      English
      Type
      Thesis
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      Abstract
      Nature is an inspirational school for materials scientists. Natural selection process puts a massive pressure on biological organisms giving rise to effective strategies for fabricating materials, which generally outperform their man-made counterparts. Mimicking physical and chemical features of biological materials can greatly aid in overcoming existing design constraints of engineering and medicine. In this dissertation, a reductionist, bottom-up approach is demonstrated to recapitulate biological functionalities in fully-synthetic hybrid constructs. For material design, the potential of short, rationally-designed peptides for programmed organization into nanostructured materials is explored. The resulting nano-ordered materials exhibit multifunctional and adaptive properties, which can be tailored by the information within monomeric peptide sequences as well as the emerging properties upon their self-assembly. In light of these, design, synthesis and characterization of the prototypes of nanostructured functional materials are described in the context of regenerative medicine and biomineralization.
      Keywords
      Bioinspired Materials
      Functional Self-Assembly
      Biomaterials
      Surface Functionalization
      Biomineralization
      Permalink
      http://hdl.handle.net/11693/17088
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      • Graduate Program in Materials Science and Nanotechnology - Ph.D. / Sc.D. 75
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