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      • Department of Molecular Biology and Genetics
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      Forging a potent vaccine adjuvant: CpG ODN/cationic peptide nanorings

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      Author(s)
      Gungor, B.
      Yagci, F. C.
      Gursel, I.
      Gursel, M.
      Date
      2014-07
      Source Title
      Oncolmmunology
      Electronic ISSN
      2162-402X
      Publisher
      Taylor & Francis Inc.
      Volume
      3
      Issue
      7
      Pages
      950166-1 - 950166-3
      Language
      English
      Type
      Article
      Item Usage Stats
      128
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      Abstract
      Type I interferon inducers may potentially be engineered to function as antiviral and anticancer agents, or alternatively, vaccine adjuvants, all of which may have clinical applications. We recently described a simple strategy to convert a Toll-like receptor 9 (TLR9) agonist devoid of interferon alpha (IFN alpha) stimulating activity into a robust Type I interferon inducer with potent vaccine adjuvant activity.
      Keywords
      Cpg Odn
      Type I Interferon
      Vaccine Adjuvant
      Dendritic Cells
      Oligodeoxynucleotides
      Activation
      Induction
      Permalink
      http://hdl.handle.net/11693/12613
      Published Version (Please cite this version)
      http://dx.doi.org/10.4161/21624011.2014.950166
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