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      Designing BODIPY-based probes for fluorescence imaging of b-amyloid plaques

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      Author(s)
      Sozmen, F.
      Kolemen, S.
      Kumada, H. O.
      Ono, M.
      Saji, H.
      Akkaya, E. U.
      Date
      2014
      Source Title
      RSC Advances
      Print ISSN
      2046-2069
      Publisher
      Royal Society of Chemistry
      Volume
      4
      Issue
      92
      Pages
      51032 - 51037
      Language
      English
      Type
      Article
      Item Usage Stats
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      Abstract
      Styryl-congutated BODIPY dyes which are structurally similar to known Ab peptide binding dyes, were designed and synthesized. The binding is accompanied by a large increase in the emission intensity in all cases, suggesting a high potential for use in the fluorescence imaging of Ab plaques.
      Keywords
      Photodynamic Therapy
      Protein Aggregation
      Dyes
      Neurodegeneration
      Hotosensitizers
      Therapeutics
      Derivatives
      Permalink
      http://hdl.handle.net/11693/12595
      Published Version (Please cite this version)
      http://dx.doi.org/10.1039/c4ra07754g
      Collections
      • Department of Chemistry 640
      • Institute of Materials Science and Nanotechnology (UNAM) 1930
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