Designing BODIPY-based probes for fluorescence imaging of b-amyloid plaques
Date
2014Source Title
RSC Advances
Print ISSN
2046-2069
Publisher
Royal Society of Chemistry
Volume
4
Issue
92
Pages
51032 - 51037
Language
English
Type
ArticleItem Usage Stats
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Abstract
Styryl-congutated BODIPY dyes which are structurally similar to known Ab peptide binding dyes, were
designed and synthesized. The binding is accompanied by a large increase in the emission intensity in all
cases, suggesting a high potential for use in the fluorescence imaging of Ab plaques.
Keywords
Photodynamic TherapyProtein Aggregation
Dyes
Neurodegeneration
Hotosensitizers
Therapeutics
Derivatives