Control charts with exponentially weighted moving average (EWMA) statistics (mean and variance) are used to jointly monitor the mean and variance of a process. An EWMA cost minimization model is presented to design the joint control scheme based on pure economic or both economic and statistical performance criteria. The pure economic model is extended to the economic-statistical design by adding constraints associated with in-control and out-of-control average run lengths. The quality related production costs are calculated using Taguchi's quadratic loss function. The optimal values of smoothing constants, sampling interval, sample size, and control chart limits are determined by using a numerical search method. The average run length of the control scheme is computed by using the Markov chain approach. Computational study indicates that optimal sample sizes decrease as the magnitudes of shifts in mean and/or variance increase, and higher values of quality loss coefficient lead to shorter sampling intervals. The sensitivity analysis results regarding the effects of various inputs on the chart parameters provide useful guidelines for designing an EWMA-based process control scheme when there exists an assignable cause generating concurrent changes in process mean and variance. (C) 2006 Elsevier B.V. All rights reserved.