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      Biomimetic cell membrane-coated poly(lactic-co-glycolic acid) nanoparticles for biomedical applications

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      Author(s)
      Jan, N.
      Madni, A.
      Khan, S.
      Shah, H.
      Akram, F.
      Khan, A.
      Ertas, D.
      Bostanudin, M. F.
      Contag, C. H.
      Ashammakhi, N.
      Ertaş, Yavuz Nuri
      Date
      2022-11-02
      Source Title
      Bioengineering & Translational Medicine
      Electronic ISSN
      2380-6761
      Publisher
      John Wiley & Sons, Inc.
      Pages
      1 - 36
      Language
      English
      Type
      Review
      Item Usage Stats
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      15
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      Abstract
      Poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) are commonly used for drug delivery because of their favored biocompatibility and suitability for sustained and controlled drug release. To prolong NP circulation time, enable target-specific drug delivery and overcome physiological barriers, NPs camouflaged in cell membranes have been developed and evaluated to improve drug delivery. Here, we discuss recent advances in cell membrane-coated PLGA NPs, their preparation methods, and their application to cancer therapy, management of inflammation, treatment of cardiovascular disease and control of infection. We address the current challenges and highlight future research directions needed for effective use of cell membrane-camouflaged NPs
      Keywords
      Biodegradable
      Biomimetic
      Cell-membrane
      Drug delivery
      PLGA
      Targeted delivery
      Permalink
      http://hdl.handle.net/11693/111940
      Published Version (Please cite this version)
      https://dx.doi.org/10.1002/btm2.10441
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      • Institute of Materials Science and Nanotechnology (UNAM) 2258
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