dc.contributor.author | Algın, Oktay | |
dc.contributor.author | Ayberk, G. | |
dc.date.accessioned | 2023-02-21T14:04:16Z | |
dc.date.available | 2023-02-21T14:04:16Z | |
dc.date.issued | 2022-07 | |
dc.identifier.issn | 1867-1071 | |
dc.identifier.uri | http://hdl.handle.net/11693/111594 | |
dc.description.abstract | Background and purpose: An accurate histopathological examination with minimal neuronal damage is essential for optimizing treatment strategies of central nervous system lesions. We investigated the feasibility and safety of CT and 3-tesla (3 T) MR-guided freehand brain aspiration biopsies with 18/20-gauge coaxial needles in performing a single imaging unit. Materials and methods: We reviewed CT and 3 T-MR guided freehand aspiration biopsies with 18/20-gauge coaxial needles of 33 patients (11-female and 22-male, mean and median ages: 53 years, min–max 21–79 years) in our tertiary hospital within an 8-year-period were included in this retrospective study. Lesion sizes, diagnostic yield, morbidity, and mortality rates of these biopsies without a scalp incision, surgical burr-hole, or stereotactic-instrumentation/neuro-navigation guidance were assessed. All biopsies were performed with local anesthesia and sedation within a single imaging unit of our radiology department. All free-hand biopsies were done as in-patient procedures and the patients were closely observed after the biopsies. Results: The mean diameter of the lesions was 27 mm (median 25; range 15–46 mm). The diagnostic yield of all free-hand brain biopsies was 88% [one inconclusive result (90%) for 3 T-MR; three inconclusive results (87%) for CT]. There was no major hemorrhage or hematoma, no clinical deterioration, or no infection in our patients on early- and late-phase examinations. Postprocedural minor hemorrhage with a ≤ 2 cm diameter was observed in two patients. The morbidity rate of the study population is 6%. There was no procedure-related infection or mortality in the post-procedural 3 weeks. Conclusions: Freehand CT or 3 T-MR guided aspiration biopsy was a safe and feasible method for pathological diagnosis of intracranial lesions. Biopsy workflow was simplified with this technique. It could be considered a valuable alternative for stereotaxic biopsies, especially for centers that do not have stereotaxic equipment or experience. © 2022, The Author(s) under exclusive licence to Japan Radiological Society. | en_US |
dc.language.iso | English | en_US |
dc.source.title | Japanese Journal of Radiology | en_US |
dc.relation.isversionof | https://doi.org/10.1007/s11604-022-01257-2 | en_US |
dc.subject | 3-tesla (3T) | en_US |
dc.subject | Brain biopsy | en_US |
dc.subject | Central nervous system | en_US |
dc.subject | Lymphoma | en_US |
dc.subject | MRI | en_US |
dc.subject | Tumors | en_US |
dc.title | Feasibility of freehand CT and 3-T MR guided brain aspiration biopsies with 18/20-gauge coaxial needles | en_US |
dc.type | Article | en_US |
dc.department | Aysel Sabuncu Brain Research Center (BAM) | en_US |
dc.department | National Magnetic Resonance Research Center (UMRAM) | en_US |
dc.citation.spage | 740 | en_US |
dc.citation.epage | 748 | en_US |
dc.citation.volumeNumber | 40 | en_US |
dc.citation.issueNumber | 7 | en_US |
dc.identifier.doi | 10.1007/s11604-022-01257-2 | en_US |
dc.publisher | Springer | en_US |
dc.contributor.bilkentauthor | Algın, Oktay | |
buir.contributor.orcid | Algın, Oktay|0000-0002-3877-8366 | en_US |