System for MR image-guided prostate interventions: Canine study
Author(s)
Date
2003Source Title
Radiology
Print ISSN
0033-8419
Publisher
Radiological Society of North America, Inc. Radiological Society of North America, Inc.
Volume
228
Issue
3
Pages
886 - 894
Language
English
Type
ArticleItem Usage Stats
225
views
views
166
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downloads
Abstract
The purpose of this study was to demonstrate the use of a transrectal system that enables precise magnetic resonance (MR) image guidance and monitoring of prostate interventions. The system used a closed-bore 1.5-T MR imaging unit and enables one to take advantage of the higher signal-to-noise ratio achieved with traditional magnet designs, which is crucial for accurate targeting and monitoring of prostate interventions. In the first of the four canine studies, reliable needle placement, with all needles placed within 2 mm of the desired target site, was achieved. In two other studies, MR imaging was used to monitor distribution of injected contrast agent solution (gadopentetate dimeglumine mixed with trypan blue dye) in and around the prostate, thereby confirming that solution had been delivered to the desired tissue and also detecting faulty injections. In the final study, accurate placement and MR imaging of brachytherapy seeds in the prostate were demonstrated. The described system provides a flexible platform for a variety of minimally invasive MR image-guided therapeutic and diagnostic prostate interventions. © RSNA, 2003.
Keywords
Magnetic resonance (MR), experimental studiesMagnetic resonance (MR), guidance
Prostate neoplasms
Prostate neoplasms, MR
Prostate neoplasms, therapeutic radiology
Gadolinium pentetate meglumine
Trypan blue
Accuracy
Animal experiment
Brachytherapy
Contrast enhancement
Diagnostic approach route
Dog
Equipment design
Image analysis
Image enhancement
Image processing
Magnet
Needle
Nonhuman
Nuclear magnetic resonance imaging
Prostate disease
Signal noise ratio
Animals
Brachytherapy
Contrast Media
Dogs
Gadolinium DTPA
Injections, Intralesional
Magnetic Resonance Imaging
Male
Prostate
Prostatic Neoplasms
Trypan Blue
Permalink
http://hdl.handle.net/11693/24432Published Version (Please cite this version)
http://dx.doi.org/10.1148/radiol.2283020911Collections
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