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      System for MR image-guided prostate interventions: Canine study

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      Author(s)
      Susil, R. C.
      Krieger, A.
      Derbyshire, J. A.
      Tanacs, A.
      Whitcomb, L. L.
      Fichtinger, G.
      Atalar, Ergin
      Date
      2003
      Source Title
      Radiology
      Print ISSN
      0033-8419
      Publisher
      Radiological Society of North America, Inc.
       
      Radiological Society of North America, Inc.
       
      Volume
      228
      Issue
      3
      Pages
      886 - 894
      Language
      English
      Type
      Article
      Item Usage Stats
      225
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      166
      downloads
      Abstract
      The purpose of this study was to demonstrate the use of a transrectal system that enables precise magnetic resonance (MR) image guidance and monitoring of prostate interventions. The system used a closed-bore 1.5-T MR imaging unit and enables one to take advantage of the higher signal-to-noise ratio achieved with traditional magnet designs, which is crucial for accurate targeting and monitoring of prostate interventions. In the first of the four canine studies, reliable needle placement, with all needles placed within 2 mm of the desired target site, was achieved. In two other studies, MR imaging was used to monitor distribution of injected contrast agent solution (gadopentetate dimeglumine mixed with trypan blue dye) in and around the prostate, thereby confirming that solution had been delivered to the desired tissue and also detecting faulty injections. In the final study, accurate placement and MR imaging of brachytherapy seeds in the prostate were demonstrated. The described system provides a flexible platform for a variety of minimally invasive MR image-guided therapeutic and diagnostic prostate interventions. © RSNA, 2003.
      Keywords
      Magnetic resonance (MR), experimental studies
      Magnetic resonance (MR), guidance
      Prostate neoplasms
      Prostate neoplasms, MR
      Prostate neoplasms, therapeutic radiology
      Gadolinium pentetate meglumine
      Trypan blue
      Accuracy
      Animal experiment
      Brachytherapy
      Contrast enhancement
      Diagnostic approach route
      Dog
      Equipment design
      Image analysis
      Image enhancement
      Image processing
      Magnet
      Needle
      Nonhuman
      Nuclear magnetic resonance imaging
      Prostate disease
      Signal noise ratio
      Animals
      Brachytherapy
      Contrast Media
      Dogs
      Gadolinium DTPA
      Injections, Intralesional
      Magnetic Resonance Imaging
      Male
      Prostate
      Prostatic Neoplasms
      Trypan Blue
      Permalink
      http://hdl.handle.net/11693/24432
      Published Version (Please cite this version)
      http://dx.doi.org/10.1148/radiol.2283020911
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      • Department of Electrical and Electronics Engineering 4011
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