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dc.contributor.authorOkay O.en_US
dc.contributor.authorDaglioglu, E.en_US
dc.contributor.authorYakicier, C.en_US
dc.contributor.authorUren, D.en_US
dc.contributor.authorDalgic, A.en_US
dc.contributor.authorErgungor F.en_US
dc.date.accessioned2016-02-08T10:01:26Z
dc.date.available2016-02-08T10:01:26Z
dc.date.issued2009en_US
dc.identifier.issn10195149
dc.identifier.urihttp://hdl.handle.net/11693/22540
dc.description.abstractChoroid plexus papilloma (CPP) is a rare, benign epithelial brain tumor of the nervous system seen particularly in infants. Familial cases are extremely uncommon. Some other form of malignant tumors was noted in the relatives of patients with CPPs, and some genetic defects regarding this coincidence were reported in the literature. These neoplasms are occasionally bilateral and hydrocephalus is an associated sign in most of the cases. We report three lateral ventricle CPPs in two siblings, at the age of 7 month and 2 years respectively. All tumors were resected with parietotemporal craniotomy and a superior temporal sulcus approach to the lateral ventricle. To avoid a concomitant need of ventriculoperitoneal shunt insertion, external ventricular drainage was inserted for a week in the postoperative period relieving symptoms of hydrocephalus. Search for a hereditary defect in the p53 gene of the second infant (7 months old) revealed no mutation. Postoperative courses were uneventful and the patients were followed for three years without any recurrence. Bilateral CPPS are rare and unusual in two siblings. A genetic predisposition such as the p53 mutation should be investigated in bilateral CPPs in particular.en_US
dc.language.isoTurkishen_US
dc.source.titleTurkish Neurosurgeryen_US
dc.subjectChoroid plexusen_US
dc.subjectFamiliaren_US
dc.subjectHydrocephalusen_US
dc.subjectLateral Ventricleen_US
dc.subjectp53-Mutationen_US
dc.subjectPapillomaen_US
dc.subjectprotein p53en_US
dc.subjectarticleen_US
dc.subjectbrain ventricle peritoneum shunten_US
dc.subjectcase reporten_US
dc.subjectchoroid plexus papillomaen_US
dc.subjectgeneticsen_US
dc.subjecthumanen_US
dc.subjecthydrocephalusen_US
dc.subjectinfanten_US
dc.subjectlateral brain ventricleen_US
dc.subjectmaleen_US
dc.subjectmolecular geneticsen_US
dc.subjectnuclear magnetic resonance imagingen_US
dc.subjectnucleotide sequenceen_US
dc.subjectpathologyen_US
dc.subjectpreschool childen_US
dc.subjectsiblingen_US
dc.subjectBase Sequenceen_US
dc.subjectChild, Preschoolen_US
dc.subjectHumansen_US
dc.subjectHydrocephalusen_US
dc.subjectInfanten_US
dc.subjectLateral Ventriclesen_US
dc.subjectMagnetic Resonance Imagingen_US
dc.subjectMaleen_US
dc.subjectMolecular Sequence Dataen_US
dc.subjectPapilloma, Choroid Plexusen_US
dc.subjectSiblingsen_US
dc.subjectTumor Suppressor Protein p53en_US
dc.subjectVentriculoperitoneal Shunten_US
dc.titleChoroid Plexus Papillomas in two Siblings: Case Reporten_US
dc.title.alternativeİki Kardeşte Görülen Koroid Pleksus Papillomu: Olgu Sunumuen_US
dc.typeArticleen_US
dc.departmentDepartment of Molecular Biology and Genetics
dc.citation.spage281en_US
dc.citation.epage284en_US
dc.citation.volumeNumber19en_US
dc.citation.issueNumber3en_US


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