Now showing items 1-6 of 6
Angiogenic peptide nanofibers improve wound healing in STZ-induced diabetic rats
(American Chemical Society, 2016-06)
Low expressions of angiogenic growth factors delay the healing of diabetic wounds by interfering with the process of blood vessel formation. Heparin mimetic peptide nanofibers can bind to and enhance production and activity ...
A glycosaminoglycan mimetic peptide nanofiber gel as an osteoinductive scaffold
(Royal Society of Chemistry, 2016)
Biomineralization of the extracellular matrix (ECM) plays a crucial role in bone formation. Functional and structural biomimetic native bone ECM components can therefore be used to change the fate of stem cells and induce ...
Local delivery of doxorubicin through supramolecular peptide amphiphile nanofiber gels
(Royal Society of Chemistry, 2017)
Peptide amphiphiles (PAs) self-assemble into supramolecular nanofiber gels that provide a suitable environment for encapsulation of both hydrophobic and hydrophilic molecules. The PA gels have significant advantages for ...
Angiogenic heparin-mimetic peptide nanofiber gel improves regenerative healing of acute wounds
(American Chemical Society, 2017)
Wound repair in adult mammals typically ends with the formation of a scar, which prevents full restoration of the function of the healthy tissue, although most of the wounded skin heals. Rapid and functional recovery of ...
Heparin mimetic peptide nanofiber gel promotes regeneration of full thickness burn injury
(Elsevier Ltd, 2017)
Burn injuries are one of the most common types of trauma worldwide, and their unique physiology requires the development of specialized therapeutic materials for their treatment. Here, we report the use of synthetic, ...
Laminin mimetic peptide nanofibers regenerate acute muscle defect
(Acta Materialia Inc, 2017)
Skeletal muscle cells are terminally differentiated and require the activation of muscle progenitor (satellite) cells for their regeneration. There is a clinical need for faster and more efficient treatment methods for ...