Browsing by Keywords "tumor growth"

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The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity

Sag, D.; Cekic, C.; Wu, R.; Linden J.; Hedrick, C.C. (Nature Publishing Group, 2015)

ATP-binding cassette transporter G1 (ABCG1) promotes cholesterol efflux from cells and regulates intracellular cholesterol homeostasis. Here we demonstrate a role of ABCG1 as a mediator of tumour immunity. Abcg1-/- mice ...