Browsing by Keywords "p16INK4a"
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Acquired expression of transcriptionally active p73 in hepatocellular carcinoma cells
(Nature Publishing Group, 2001)p53 and p73 proteins activate similar target genes and induce apoptosis and cell cycle arrest. However, p53, but not p73 is considered a tumour-suppressor gene. Unlike p53, p73 deficiency in mice does not lead to a ...