Browsing by Keywords "lncRNA"
Now showing items 1-3 of 3
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Discovering competing endogenous RNA interactions in breast cancer molecular subtypes
(Springer, 2018)Background: Long non-coding RNAs (lncRNAs) can indirectly regulate mRNAs expression levels by sequestering microRNAs (miRNAs), and act as competing endogenous RNAs (ceRNAs) or as sponges. Previous studies identified ... -
Discovering regulatory non-coding RNA interactions
(Bilkent University, 2019-09)The vast majority of eukaryotic transcriptomes comprise noncoding RNAs (ncRNAs) which are not translated into proteins. Despite the accumulating evidence on the functional roles of ncRNAs, we are still far from understanding ... -
Identification of long non-coding RNAs overcoming tamoxifen resistance in estrogen receptor alpha positive breast cancer
(Bilkent University, 2017-09)Most of the breast cancer incidences all over the world fall into Estrogen Receptor alpha (ERα)-positive breast cancer subtype, which are treated with endocrine therapy. Tamoxifen, a selective ER modulator drug, is the ...
