Now showing items 1-3 of 3

    • Benzothiazole derivatives as human DNA topoisomerase IIα inhibitors 

      Kaplan-Ozen, C.; Tekiner-Gulbas, B.; Foto, E.; Yildiz I.; Diril, N.; Aki, E.; Yalcin I. (2013)
      Benzothiazole derivatives resembling the structure of DNA purine bases were tested to determine their topoisomerase inhibition activities. Based on DNA topoisomerase I and II relaxation assay results, all 12 derivatives ...
    • Cytotoxic activities of some benzothiazole-piperazine derivatives 

      Gurdal, E.E.; Durmaz I.; Cetin-Atalay, R.; Yarim, M. (Taylor and Francis Ltd, 2015)
      Synthesis, characterization and cytotoxic activities of ten benzothiazole-piperazine derivatives were reported. In vitro cytotoxic activities of compounds were screened against hepatocellular (HUH-7), breast (MCF-7) and ...
    • Synthesis and anticancer activity evaluation of some benzothiazole-piperazine derivatives 

      Gurdal, E.E.; Buclulgan, E.; Durmaz I.; Cetin-Atalay, R.; Yarim, M. (Bentham Science Publishers B.V., 2015)
      Synthesis, characterization and cytotoxic activities of ten benzothiazole-piperazine derivatives were reported. In vitro cytotoxic activities of compounds were screened against hepatocellular (HUH-7), breast (MCF-7) and ...