Browsing by Keywords "Up-regulation"

Now showing items 1-2 of 2

    • CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1 

      Ligons, D. L.; Tuncer, C.; Linowes, B. A.; Akcay, I. M.; Kurtulus, S.; Deniz, E.; Arslan, B. A.; Cevik, S. I.; Keller, H. R.; Luckey, M. A.; Feigenbaum, L.; Möröy, T.; Ersahin, T.; Atalay, R.; Erman, B.; Park, J. H. (The American Society for Biochemistry and Molecular Biology, Inc., 2012)
      Interleukin-7 receptor α (IL-7Rα) is essential for T cell survival and differentiation. Glucocorticoids are potent enhancers of IL-7Rα expression with diverse roles in T cell biology. Here we identify the transcriptional ...

    • Senescence and immortality in hepatocellular carcinoma 

      Ozturk, M.; Arslan-Ergul, A.; Bagislar, S.; Senturk, S.; Yuzugullu, H. (Elsevier, 2009-10-01)
      Cellular senescence is a process leading to terminal growth arrest with characteristic morphological features. This process is mediated by telomere-dependent, oncogene-induced and ROS-induced pathways, but persistent DNA ...