Browsing by Keywords "UPR"
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Lipotoxic endoplasmic reticulum stress-associated inflammation : molecular mechanisms and modification by a bioactive lipokine
(Bilkent University, 2012)Physiologic or pathologic processes that disturb protein folding in the endoplasmic reticulum (ER) activate a signaling pathway named the unfolded protein response (UPR). UPR promotes cell survival by reducing misfolded ... -
The role of Protein Kinase R in lipotoxicity
(Bilkent University, 2013)Endoplasmic reticulum (ER) is a central organelle for cellular homeostasis through its myriad of functions including protein and lipid biosynthesis, protein folding and secretion and calcium homeostasis. When protein ... -
Unfolded protein response regulated mirnas in lipotoxic endoplasmic reticulum stress in macrophages
(Bilkent University, 2014-07)The proper functioning and the development of the cell is essential to the fitness of the multicellular organisms - any significant disturbances in cellular mechanisms can lead to a multitude of diseases or death. Among ...
