Browsing by Keywords "Schizophrenia"

Now showing items 1-20 of 20

    • The Association between familial risk and brain abnormalities Is disease specific: an ENIGMA-relatives study of schizophrenia and bipolar disorder 

      Zwarte, S. M. C.; Brouwer, R. M.; Agartz, I.; Alda, M.; Aleman, A.; Alpert, K. I.; Bearden, C. E.; Bertolino, A.; Bois, C.; Bonvino, A.; Bramon, E.; Buimer, E.; Cahn, W.; Cannon, D. M.; Cannon, T. D.; Caseras, X.; Castro-Fornieles, J.; Chen, Q.; Serna, E.; Giorgio, A. D.; Doucet, G.; Eker, M. C.; Erk, S.; Fears, S.; Foley, S.; Frangou, S.; Frankland, A.; Fullerton, J.; Glahn, D.; Goghari, V.; Goldman, A.; Gonul, A.; Gruber, O.; Haan, L.; Hajek, T.; Hawkins, E.; Heinz, A.; Hillegers, M.; Pol, H.; Hultman, C.; Ingvar, M.; Johansson, V.; Jönsson, E.; Kane, K.; Kempton, M.; Koenis, M.; Kopecek, M.; Krabbendam, L.; Krämer, B.; Lawrie, S.; Lenroot, R.; Marcelis, M.; Marsman, J-B; Mattay, V.; McDonald, C.; Meyer-Lindenberg, A.; Michielse, S.; Mitchell, P.; Moreno, D.; Murray, R.; Mwangi, B.; Najt, P.; Neilson, E.; Newport, J.; Os, J.; Overs, B.; Özerdem, A.; Picchioni, M.; Richter, A.; Roberts, G.; Aydoğan, A. S.; Schofield, P.; Şimşek, F.; Soares, J.; Sugranyes, G.; Toulopoulou, Timothea; Tronchin, G.; Walter, H.; Wang, L.; Weinberger, D.; Whalley, H.; Yalın, N.; Andreassen, O.; Ching, C.; Erp, T.; Turner, J.; Jahanshad, N.; Thompson, P.; Kahn, R.; Haren, N. (Elsevier, 2019)
      Abstract Background Schizophrenia and bipolar disorder share genetic liability, and some structural brain abnormalities are common to both conditions. First-degree relatives of patients with schizophrenia (FDRs-SZ) show ...

    • Associations between psychosis endophenotypes across brain functional, structural, and cognitive domains 

      Blakey, R.; Ranlund, S.; Zartaloudi, E.; Cahn, W.; Calafato, S.; Colizzi, M.; Crespo-Facorro, B.; Daniel, C.; Díez-Revuelta, A.; Forti, M. D.; Iyegbe, C.; Jablensky, A.; Jones, R.; Hall, M. -H.; Kahn, R.; Kalaydjieva, L.; Kravariti, E.; Lin, K.; McDonald, C.; McIntosh, A. M.; Picchioni, M.; Powell, J.; Presman, A.; Rujescu, D.; Schulze, K.; Shaikh, M.; Thygesen, J. H.; Toulopoulou, Timothea; Haren, N. V.; Os, J. V.; Walshe, M.; Murray, R. M.; Bramon, E. (Cambridge University Press, 2018)
      Background A range of endophenotypes characterise psychosis, however there has been limited work understanding if and how they are inter-related.Methods This multi-centre study includes 8754 participants: 2212 people with ...

    • Beckett'in ayak sesleri adlı tiyatro eserinde zihinde yankılanmalar 

      Bayrakçeken-Akın, Aylin (Ürün Yayınları, 2016)
      Footfalls was written by Saınuel Beckett in 1975 and was first peıfoımed at the Royal Court Theah·e as part of the Samuel Beckett Festival on May 20, 1976. The play was directed by Beckett himself. There are two characters. ...

    • Dynamic alternative splicing events in the dorsolateral prefrontal cortex during adolescence-young adulthood period and implications for schizophrenia 

      Çelikbaş, Kübra (Bilkent University, 2020-12)
      Alternative splicing (AS) or differential exon usage (DEU) is a regular process after gene expression and it contributes to the diversity of the genome by generating multiple protein isoforms. According to recent studies, ...

    • Effect of clozapine on white matter integrity in patients with schizophrenia: a diffusion tensor imaging study 

      Ozcelik-Eroglu, E.; Ertugrul, A.; Oguz, K. K.; Has, A. C.; Karahan, S.; Yazici, M. K. (Elsevier, 2014)
      Several diffusion tensor imaging (DTI) studies have reported disturbed white matter integrity in various brain regions in patients with schizophrenia, whereas only a few studied the effect of antipsychotics on DTI measures. ...

    • The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) consortium: a collaborative cognitive and neuroimaging genetics project 

      Blokland, G. A. M.; Del Re, E. C.; Mesholam-Gately, R. I.; Jovicich, J.; Trampush, J. W.; Keshavan, M. S.; DeLisi, L. E.; Walters, J. T. R.; Turner, J. A.; Malhotra, A. K.; Lencz, T.; Shenton, M. E.; Voineskos, A. N.; Rujescu, D.; Giegling, I.; Kahn, R. S.; Roffman, J. L.; Holt, D. J.; Ehrlich, S.; Kikinis, Z.; Dazzan, P.; Murray, R. M.; Di Forti, M.; Lee, J.; Sim, K.; Lam, M.; Wolthusen, R. P. F.; De Zwarte, S. M. C.; Walton, E.; Cosgrove, D.; Kelly, S.; Maleki, N.; Osiecki, L.; Picchioni, M. M.; Bramon, E.; Russo, M.; David, A. S.; Mondelli, V.; Reinders, A. A. T. S.; Falcone, M. A.; Hartmann, A. M.; Konte, B.; Morris, D. W.; Gill, M.; Corvin, A. P.; Cahn, W.; Ho, N. F.; Liu, J. J.; Keefe, R. S. E.; Gollub, R. L.; Manoach, D. S.; Calhoun, V. D.; Schulz, S. C.; Sponheim, S. R.; Goff, D. C.; Buka, S. L.; Cherkerzian, S.; Thermenos, H. W.; Kubicki, M.; Nestor, P. G.; Dickie, E. W.; Vassos, E.; Ciufolini, S.; Marques, T. R.; Crossley, N. A.; Purcell, S. M.; Smoller, J. W.; Van Haren, N. E. M.; Toulopoulou, Timothea; Donohoe, G.; Goldstein, J. M.; Seidman, L. J.; McCarley, R. W.; Petryshen, T. L. (Elsevier, 2018)
      Background: Schizophrenia has a large genetic component, and the pathways from genes to illness manifestation are beginning to be identified. The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia ...

    • The impact of psychosis genome-wide associated ZNF804A variation on verbal fluency connectivity 

      Tecelão, D.; Mendes, A.; Martins, D.; Bramon, E.; Toulopoulou, Timothea; Kravariti, E.; Murray, R.; Prata, D. (Elsevier, 2018)
      Schizophrenia (SCZ) and bipolar disorder (BD) have high heritability. Genome-wide association studies (GWAS) have identified ZNF804A as a significant risk gene for both illnesses. A validation of this finding at the brain ...

    • Integrated assessment of visual perception abnormalities in psychotic disorders and relationship with clinical characteristics 

      Türközer, H. B.; Hasoğlu, T.; Chen, Y.; Norris, L. A.; Brown, M.; Delaney-Busch, N.; Kale, E. H.; Pamir, Zahide; Boyacı, Hüseyin; Kuperberg, G.; Lewandowski, K. E.; Topçuoğlu, V.; Öngür, D. (Cambridge University Press, 2019)
      Background-The visual system is recognized as an important site of pathology and dysfunction in schizophrenia. In this study, we evaluated different visual perceptual functions in patients with psychotic disorders using a ...

    • Intelligence, educational attainment, and brain structure in those at familial high‐risk for schizophrenia or bipolar disorder 

      de Zwarte, S. M. C.; Brouwer, R.; Agartz, I.; Alda, M.; Alonso-Lana, S.; Bearden, C.; Bertolino, A.; Bonvino, A.; Bramon, E.; Buimer, E.; Cahn, W.; Canales-Rodríguez, E.; Cannon, D. M.; Cannon, T. D.; Caseras, X.; Castro-Fornieles, J.; Chen, Q.; Chung, Y.; De la Serna, E.; del Mar Bonnin, C.; Demro, C.; Di Giorgio, A.; Doucet, G.; Eker, M.; Erk, S.; Fatjó-Vilas, M.; Fears, S.; Foley, S.; Frangou, S.; Fullerton, J.; Glahn, D.; Goghari, V.; Goikolea, J.; Goldman, A.; Gonul, A.; Gruber, O.; Hajek, T.; Hawkins, E.; Heinz, A.; Ongun, C.; Hillegers, M.; Houenou, J.; Pol, H.; Hultman, C.; Ingvar, M.; Johansson, V.; Jönsson, E.; Kane, F.; Kempton, M.; Koenis, M.; Kopecek, M.; Krämer, B.; Lawrie, S.; Lenroot, R.; Marcelis, M.; Mattay, V.; McDonald, C.; Meyer-Lindenberg, A.; Michielse, S.; Mitchell, P.; Moreno, D.; Murray, R.; Mwangi, B.; Nabulsi, L.; Newport, J.; Olman, C.; van Os, J.; Overs, B.; Ozerdem, A.; Pergola, G.; Picchioni, M.; Piguet, C.; Pomarol-Clotet, E.; Radua, J.; Ramsay, I.; Richter, A.; Roberts, G.; Salvador, R.; Saricicek-Aydogan, A.; Sarró, S.; Schofield, P.; Simsek, E.; Simsek, F.; Soares, J.; Sponheim, S.; Sugranyes, G.; Toulopoulou, Timothea; Tronchin, G.; Vieta, E.; Walter, H.; Weinberger, D.; Whalley, H.; Wu, M. -J.; Yalin, N.; Andreassen, O.; Ching, C.; Thomopoulos, S.; van Erp, T.; Jahanshad, N.; Thompson, P.; Kahn, R.; van Haren, N. (Wiley, 2020)
      First‐degree relatives of patients diagnosed with schizophrenia (SZ‐FDRs) show similar patterns of brain abnormalities and cognitive alterations to patients, albeit with smaller effect sizes. First‐degree relatives of ...

    • Intrinsic oscillations of auditory networks in schizophrenia and bipolar disorder 

      Atagün, M. İ.; Akın, B.; Algın, Oktay; Sıkoğlu, E. M.; Can, S. S.; Kaymak, S. U.; Çayköylü, A.; Moore, C.; Phillips, M.; Ongur, D. (Yerküre Tanıtım ve Yayıncılık Hizmetleri A. Ş., 2019)
      Objective: Several types of evidence have shown that auditory networks are dysfunctional in schizophrenia (Sch) and bipolar disorders (BD). Auditory cortices show abnormalities in hallucinations or during remission. This ...

    • Investigation of Heschl's gyrus and planum temporale in patients with schizophrenia and bipolar disorder: a proton magnetic resonance spectroscopy study 

      Atagün, M. İ.; Şıkoğlu, E. M.; Can, S. S.; Karakaş-Uğurlu, G.; Ulusoy-Kaymak, S.; Çayköylü, A.; Algın,Oktay; Phillips, M. L.; Moore, C. M.; Öngür, D. (Elsevier, 2015)
      Background: Superior temporal cortices include brain regions dedicated to auditory processing and several lines of evidence suggest structural and functional abnormalities in both schizophrenia and bipolar disorder within ...

    • Lessons learned from experiencing Mavi At Café (Blue Horse Café) during six years : a qualitative analysis of factors contributing to recovery from the perspective of schizophrenia patients 

      Soygür, Haldun; Yüksel, M. Merve; Eraslan, Pınar; Attepe Özden, Seda (Turkish Association of Nervous and Mental Health, 2017)
      Objective: In recent years, the recovery-oriented approaches (along with experiences and thoughts of patients and patient's relatives) have been taken into account for establishing mental health services and policies. This ...

    • Perisylvian GABA levels in schizophrenia and bipolar disorder 

      Atagün, M. İ.; Şıkoglu, M. E.; Soykan, Ç.; Can, S. S.; Ulusoy-Kaymak S.; Çayköylü, A.; Algın O.; Phillips, M. L.; Öngür, D.; Moore, C. M. (Elsevier Ireland Ltd, 2017)
      The aim of this study is to measure GABA levels of perisylvian cortices in schizophrenia and bipolar disorder patients, using proton magnetic resonance spectroscopy (1H-MRS). Patients with schizophrenia (n = 25), bipolar ...

    • A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains 

      Ranlund, S.; Calafato, S.; Thygesen, J. H.; Lin, K.; Cahn, W.; Crespo-Facorro, B.; Díez, A.; Forti, M. D.; Iyegbe, C.; Jablensky, A.; Jones, R.; Hall, M.; Kahn, R.; Kalaydjieva, L.; Kravariti, E.; McDonald, C.; McIntosh, A. M.; McQuillin, A.; Picchioni, M.; Prata, D. P.; Rujescu, D.; Schulze, K.; Shaikh, M.; Toulopoulou, Timothea; Haren, N.; Zwarte, S. M. C.; Os, J.; Vassos, E.; Walshe, M.; Lewis, C.; Murray, R. M.; Powell, J.; Bramon, E. (John Wiley & Sons, Inc., 2018)
      This large multi‐center study investigates the relationships between genetic risk for schizophrenia and bipolar disorder, and multi‐modal endophenotypes for psychosis. The sample included 4,242 individuals; 1,087 patients ...

    • Polygenic risk score increases schizophrenia liability through cognition-relevant pathways 

      Toulopoulou, Timothea; Zhang, X.; Cherny, S.; Dickinson, D.; Berman, K. F.; Straub, R. E.; Sham, P.; Weinberger, D. R. (Oxford University Press, 2019)
      Cognitive deficit is thought to represent, at least in part, genetic mechanisms of risk for schizophrenia, with recent evidence from statistical modelling of twin data suggesting direct causality from the former to the ...

    • Türkiye'de şizofreniye yönelik önyargının değişimi 

      Kapuağası, Burak; Erdoğan, Bengisu; Ekiz, Fatma Zehra (Bilkent University, 2020)
      Bu araştırmada Türkiye'de şizofreniye yönelik tavrın, hastalığın kamuoyu gündemine girmesinden itibaren yaşadığı değişimler ele alınmaktadır. Araştırma kapsamında; şizofreninin, psikologlar tarafından nasıl ele alındığı ...

    • Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders 

      Calafato, M. S.; Thygesen, J. H.; Ranlund, S.; Zartaloudi, E.; Cahn, W.; Crespo-Facorro, B.; Díez-Revuelta, A.; Forti, M. D.; Hall, M. -H.; Iyegbe, C.; Jablensky, A.; Kahn, R.; Kalaydjieva, L.; Kravariti, E.; Lin, K.; McDonald, C.; McIntosh, A. M.; McQuillin, A.; Picchioni, M.; Rujescu, D.; Shaikh, M.; Toulopoulou, Timothea; Os, J. V.; Vassos, E.; Walshe, M.; Powell, J.; Lewis, C. M.; Murray, R. M.; Bramon, E. (2018)
      Background There is increasing evidence for shared genetic susceptibility between schizophrenia and bipolar disorder. Although genetic variants only convey subtle increases in risk individually, their combination into a ...

    • Validation of the Chinese version of Community Assessment of Psychic Experiences (CAPE) in an adolescent general population 

      Mark, W.; Toulopoulou, T. (Elsevier B.V., 2017)
      The Community Assessment of Psychic Experiences (CAPE) is a popular 42-item self-report assessment of psychosis proneness (PP) that has been widely-translated. However, there is as yet no validation of CAPE in non-Western ...

    • A vanguard of postmodern condition: verbal and visual rhetoric in contemporary advertising 

      Şenova, Başak (Bilkent University, 1995)
      The purpose of this study is to investigate the intersections of rhetoric in advertisements with the postmodern condition and to determine if postmodern condition reflects itself in advertisements. In this context^ ...

    • Working memory circuit as a function of increasing age in healthy adolescence: a systematic review and meta-analyses 

      Andrea, J.; Picchionib, M.; Zhang, R.; Toulopoulou, T. (Elsevier Ltd, 2016-02)
      Working memoryability maturesthroughpubertyand early adulthood. Deficits inworkingmemoryare linkedtothe risk of onset of neurodevelopmental disorders such as schizophrenia, and there is a significant temporal over-lap ...