Now showing items 1-8 of 8

    • Collagen peptide presenting nanofibrous scaffold for intervertebral disc regeneration 

      Uysal, Özge; Arslan, Elif; Gülseren, Gülcihan; Kılınç, M. C.; Doğan, İ.; Özalp, H.; Çağlar, Y. Ş.; Güler, M. O.; Tekinay, Ayşe B. (American Chemical Society, 2019)
      Lower back pain (LBP) is a prevalent spinal symptom at the lumbar region of the spine, which severely effects quality of life and constitutes the number one cause of occupational disability. Degeneration of the intervertebral ...
    • Development of bioactive peptide nanofibers for intervertebral disc regeneration 

      Uysal, Özge (Bilkent University, 2017-08)
      Lower back pain (LBP) and neck problems are the most common orthopedic diseases worldwide, and the main reason behind LBP is intervertebral disc degeneration (IVDD). Therefore, specialized therapeutic applications to induce ...
    • Laminin mimetic peptide nanofibers regenerate acute muscle defect 

      Cimenci, C. E.; Uzunalli, G.; Uysal, O.; Yergoz, F.; Umay, E. K.; Güler, Mustafa O.; Tekinay, A. B. (Acta Materialia Inc, 2017)
      Skeletal muscle cells are terminally differentiated and require the activation of muscle progenitor (satellite) cells for their regeneration. There is a clinical need for faster and more efficient treatment methods for ...
    • Role of FLT3 in the proliferation and aggressiveness of hepatocellular carcinoma 

      Aydin, M. M.; Bayin, N. S.; Acun, T.; Yakicier, M. C.; Akçali, K. C. (Turkiye Klinikleri Journal of Medical Sciences, 2016)
      Background/aim: Previously we showed that Fms-like tyrosine kinase (FLT3) changes its cellular localization upon partial hepatectomy, suggesting a role in liver regeneration. FLT3 was also shown to play an important function ...
    • Role of FLT3 in the proliferation and aggressiveness of hepatocellular carcinoma 

      Aydın, Muammer Merve; Bayın, Nermin Sumru; Acun, T.; Yakıcıer, M. C.; Akçalı, K. C. (TÜBİTAK, 2016)
      Background/aim: Previously we showed that Fms-like tyrosine kinase (FLT3) changes its cellular localization upon partial hepatectomy, suggesting a role in liver regeneration. FLT3 was also shown to play an important function ...
    • Supramolecular GAG-like self-assembled glycopeptide nanofibers Induce chondrogenesis and cartilage regeneration 

      Yaylaci, U. S.; Ekiz, M. S.; Arslan, E.; Can, N.; Kilic, E.; Ozkan, H.; Orujalipoor, I.; Ide, S.; Tekinay, A. B.; Güler, Mustafa O. (American Chemical Society, 2016)
      Glycosaminoglycans (GAGs) and glycoproteins are vital components of the extracellular matrix, directing cell proliferation, differentiation, and migration and tissue homeostasis. Here, we demonstrate supramolecular GAG-like ...
    • Surface-modified bacterial nanofibrillar PHB scaffolds for bladder tissue repair 

      Karahaliloǧlu, Z.; Demirbilek, M.; Şam, M.; Saǧlam, N.; Mizrak, A. K.; Denkbaş, E. B. (Taylor and Francis Ltd., 2016)
      The aim of the study is in vitro investigation of the feasibility of surface-modified bacterial nanofibrous poly [(R)-3-hydroxybutyrate] (PHB) graft for bladder reconstruction. In this study, the surface of electrospun ...
    • Yenikapı Mevlevihanesi üzerinden tekkeler ve tekke sanatı 

      Özçelik, Elif; Aksu, Hazal; Uğuralp, Ahmet Kaan; Kahramanoğlu, Mustafa Furkan; Koca, Orkun (Bilkent University, 2018)
      Osmanlı’ da 14.yy. dan itibaren birçok tarikata ev sahipliği yapmış olan tekkelerden biri olan Yenikapı Mevlevihanesi, ibadet ve sanat gibi birçok amaç için kullanılmıştır. 1925 yılında Mustafa Kemal tarafından tekke ve ...