Now showing items 1-5 of 5

    • Interplay between 15-lipoxygenase-1 and metastasisassociated antigen 1 in the metastatic potential of colorectal cancer 

      Tunçer, S.; Çağatay, T. S.; Keşküş, A. G.; Çolakoğlu, M.; Konu, Ö.; Banerjee S. (Wiley-Blackwell Publishing Ltd., 2016)
      Objectives: Metastasis-associated antigen 1 (MTA1) is implicated in metastasis while 15-lipoxygenase-1 (15-LOX-1) reduces cell motility, when re-expressed in colorectal cancer (CRC). We aimed to understand any potential ...
    • Intestinal microbiota in patients with spinal cord injury 

      Gungor, B.; Adiguzel, E.; Gursel, I.; Yilmaz, B.; Gursel, M. (Public Library of Science, 2016)
      Human intestinal flora comprises thousands of bacterial species. Growth and composition of intestinal microbiota is dependent on various parameters, including immune mechanisms, dietary factors and intestinal motility. ...
    • mESAdb: microRNA expression and sequence analysis database 

      Kaya, Koray D.; Karakülah, G.; Yakıcıer, Cengiz M.; Acar, Aybar C.; Konu, Özlen (Oxford University Press, 2011)
      MicroRNA expression and sequence analysis database (http://konulab.fen. bilkent.edu.tr/mirna/) (mESAdb) is a regularly updated database for the multivariate analysis of sequences and expression of microRNAs from multiple ...
    • PATZ1 is a DNA damage-responsive transcription factor that inhibits p53 function 

      Keskin, N.; Deniz, E.; Eryilmaz J.; Un, M.; Batur, T.; Ersahin, T.; Atalay, R.C.; Sakaguchi, S.; Ellmeier W.; Erman, B. (American Society for Microbiology, 2015)
      Insults to cellular health cause p53 protein accumulation, and loss of p53 function leads to tumorigenesis. Thus, p53 has to be tightly controlled. Here we report that the BTB/POZ domain transcription factor PATZ1 (MAZR), ...
    • Targeting IRE1 with small molecules counteracts progression of atherosclerosis 

      Tufanli, O.; Akillilar, P. T.; Acosta-Alvear, D.; Kocaturk, B.; Onat, U. I.; Hamid, S. M.; Çimen, I.; Walter, P.; Weber, C.; Erbay, E. (National Academy of Sciences, 2017-01)
      Metaflammation, an atypical, metabolically induced, chronic lowgrade inflammation, plays an important role in the development of obesity, diabetes, and atherosclerosis. An important primer for metaflammation is the persistent ...