Browsing by Keywords "RNA polymerase II"
Now showing items 1-4 of 4
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Intronic elements in the Na+/I-symporter gene (NIS) interact with retinoic acid receptors and mediate initiation of transcription
(Oxford University Press, 2010)Activity of the sodium/iodide symporter (NIS) in lactating breast is essential for iodide (I-) accumulation in milk. Significant NIS upregulation was also reported in breast cancer, indicating a potential use of radioiodide ... -
POLR2A/RPB1 subunit of RNA polymerase II interacts with NTDMED14 containing core mediator complex to facilitate basal and activator driven transcription
(Bilkent University, 2020-06)The Metazoan Mediator is a 2-MDa protein complex that consist of 30 subunits, most of which are evolutionarily conserved from yeast to humans8. The maintenance and regulation of the cell is dependent on spatiotemporal ... -
Reconstitution of the partial tail module of the human mediator complex
(Bilkent University, 2021-09)RNA Polymerase II (Pol II) regulates and maintains every aspect of the cell through the act of transcription of protein coding genes. Transcription of protein coding genes depends on extrinsic and intrinsic signals to the ... -
Revealing the role of Med14 in Pol-II transcription regulation
(Bilkent University, 2017-08)Transcription of protein coding genes by RNA polymerase II (Pol II) is a multi-step process each of which requires a series of factors including coactivators. 30-subunit (the subunits are organized into discrete modules ...
