Browsing by Keywords "Proliferation"
Now showing items 1-7 of 7
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Assessing the genetic impact of Enterococcus faecalis infection on gastric cell line MKN74
(Springer, 2021-12)Purpose Enterococcus faecalis (E. faecalis) is an important commensal microbiota member of the human gastrointestinal tract. It has been shown in many studies that infection rates with E. faecalis in gastric cancer ... -
Effects of varying levels and differing durations of calorie restriction on cellular and synaptic proteins, as well as the inflammatory state of the female mouse brain
(Bilkent University, 2020-09)Aging is an inevitable and complicated process leading to functional decline. Regarding brain aging, cognitive decline takes place in multiple domains, including learning, memory, executive functions, motor coordination, ... -
Evaluation of ATAD2 as a potential target in hepatocellular carcinoma
(Springer, 2021-11-05)Purpose Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide with lack of effec-tive systemic chemotherapy. In this study, we aimed to evaluate the value of ATPase family AAA ... -
IKBKE inhibits TSC1 to activate the mTOR/S6K pathway for oncogenic transformation
(TUBITAK, 2018)IKBKE (IKKε) has emerged as a key modulator of multiple substrates, controlling oncogenic pathways in various malignancies. mTOR signaling, required for cellular growth, proliferation, and vascular angiogenesis in cancer, ... -
Investigation of novel RNAi and nanoparticle approaches for their anti-proliferative and drug-sensitizing effects in breast cancer
(Bilkent University, 2017-08)Drug resistivity remains a major challenge in treating different cancer types. Among several strategies adapted to increase drug sensitivity in breast cancer cells, in the present thesis I studied an RNAi molecule targeting ... -
Safety of nanomaterials
(John Wiley & Sons, 2016-03-11)This chapter overviews the attempts in understanding the biocompatibility of nanomaterials and provides an account of how these views changed in light of recent findings, with emphasis on the methodology used in nanotoxicology ... -
Thymidine dinucleotides induce S phase cell cycle arrest in addition to increased melanogenesis in human melanocytes
(1998)Although the induction of pigmentation following exposure of melanocytes to ultraviolet light in vivo and in vitro is well documented, the intracellular mechanisms involved in this response are not yet fully understood. ...
