Now showing items 1-7 of 7

    • Cancer stem cell biology 

      Chau, Tieu Lan; Xhafa, Erta; Göktuna, Serkan İsmail (Trakya Üniversitesi, 2019)
      Cancer is becoming the leading cause of death all around the world. To develop better therapeutic options against cancer, we need a thorough understanding of tumor development and dissemination. As our knowledge increases, ...
    • Energy dissipation in atomic force microscopy and atomic loss processes 

      Hoffmann, P. M.; Jeffery, S.; Pethica, J. B.; Özer, H. Ö.; Oral, A. (American Physical Society, 2001)
      Atomic scale dissipation is of great interest in nanomechanics and atomic manipulation. We present dissipation measurements with a linearized, ultrasmall amplitude atomic force microscope which is capable of measuring ...
    • Estrogen and aging affect synaptic distribution of phosphorylated LIM kinase (pLIMK) in CA1 region of female rat hippocampus 

      Yildirim, M.; Janssen, W. G. M.; Tabori, N. E.; Adams, Michelle M.; Yuen, G. S.; Akama, K. T.; McEwen, B. S.; Milner, T. A.; Morrison, J. H. (Elsevier, 2008)
      17β-Estradiol (E) increases axospinous synapse density in the hippocampal CA1 region of young female rats, but not in aged rats. This may be linked to age-related alterations in signaling pathways activated by synaptic ...
    • Growth hormone and insulin-like growth factor-I alter hippocampal excitatory synaptic transmission in young and old rats 

      Molina, D. P.; Ariwodola, O. J.; Weiner, J. L.; Bechtold, J. K. B.; Adams, Michelle M. (Age Company, 2013)
      In rats, as in humans, normal aging is characterized by a decline in hippocampal-dependent learning and memory, as well as in glutamatergic function. Both growth hormone (GH) and insulin-like growth factor-I (IGF-I) levels ...
    • A method of two-scale chemo-thermal-mechanical coupling for concrete 

      Wu, T.; Temizer, İlker; Wriggers, P. (CIMNE, 2011)
      The Alkali Silica Reaction(ASR) is one of the most important reasons to cause damage in cementitious constructions, which can be attributed to the expansion of hydrophilic gel produced in the reaction. In this contribution, ...
    • Prediction of prognosis and chemosensitivity in breast cancer 

      Akbar, Muhammad Waqas (Bilkent University, 2020-09)
      Breast cancer (BC) is responsible for the highest mortality and morbidity out of all the cancers in women which is primarily due to both inter and intra-tumoral molecular heterogeneity. This heterogeneity arises from ...
    • Regulation of Homer and group I metabotropic glutamate receptors by nicotine 

      Kane, J. K.; Hwang, Y.; Konu, O.; Loughlin, S. E.; Leslie, F. M.; Li, M. D. (Wiley-Blackwell Publishing Ltd., 2005)
      The present study focuses on the nicotine-induced modulation of mRNA and protein expression of a number of genes involved in glutamatergic synaptic transmission in rat brain over different time periods of exposure. A ...