Browsing by Keywords "Photosensitizers"
Now showing items 1-10 of 10
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Activatable photosensitizers: agents for selective photodynamic therapy
(Wiley-VCH Verlag, 2017)Recent developments in the design of bifunctional and activatable photosensitizers rejuvenate the aging field of photodynamic sensitization and photodynamic therapy. While systematic studies have uncovered new dyes that ... -
A bifunctional photosensitizer for enhanced fractional photodynamic therapy: singlet oxygen generation in the presence and absence of light
(Wiley-VCH Verlag, 2016)The photosensitized generation of singlet oxygen within tumor tissues during photodynamic therapy (PDT) is self-limiting, as the already low oxygen concentrations within tumors is further diminished during the process. In ... -
Bodipy-based photosensitizers with long alkyl tails at the meso position: efficient singlet oxygen generation in Cremophor-EL micelles
(Elsevier Ltd, 2016)Bodipy dyes with n-decyloxyphenyl-(4, 5) and pentadecyl-(8) meso substituents can easily embed themselves into micellar structures formed from Cremophor-EL. In micelles of approximately 20 nm median size, heavy-atom ... -
“Clicked” Porphyrin-cucurbituril conjugate: a new multifunctional supramolecular assembly based on triglycosylated porphyrin and Monopropargyloxycucurbit[7]uril
(Wiley-VCH Verlag, 2018)The design, synthesis, and characterization of a new multifunctional supramolecular assembly based on a photoactive glycosylated porphyrin and covalently attached monofunctionalized cucurbit[7]uril (CB7) are reported. To ... -
Near-IR absorbing BODIPY derivatives as glutathione-activated photosensitizers for selective photodynamic action
(Wiley-VCH Verlag, 2014)Enhanced spatiotemporal selectivity in photonic sensitization of dissolved molecular oxygen is an important target for improving the potential and the practical applications of photodynamic therapy. Considering the high ... -
Near-IR-triggered, remote-controlled release of metal ions: A novel strategy for caged ions
(Wiley-VCH Verlag, 2014)A ligand incorporating a dithioethenyl moiety is cleaved into fragments which have a lower metal-ion affinity upon irradiation with low-energy red/near-IR light. The cleavage is a result of singlet oxygen generation ... -
Optimization of distyryl-Bodipy chromophores for efficient panchromatic sensitization in dye sensitized solar cells
(2011)Versatility of Bodipy (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) dyes was further expanded in recent dye-sensitized solar cell applications. Here we report a series of derivatives designed to address earlier problems in ... -
PEGylated calix[4]arene as a carrier for a Bodipy-based photosensitizer
(Elsevier, 2014)Heavy atom substituted Bodipy compounds, unlike the parent chromophore, undergo rapid intersystem crossing to generate singlet oxygen, which is the primary cytotoxic agent exploited in PDT. In this work, we show that an ... -
Remote-controlled release of singlet oxygen by the plasmonic heating of endoperoxide-modified gold nanorods: towards a paradigm change in photodynamic therapy
(Wiley-VCH Verlag, 2016)The photodynamic therapy of cancer is contingent upon the sustained generation of singlet oxygen in the tumor region. However, tumors of the most metastatic cancer types develop a region of severe hypoxia, which puts them ... -
Synthesis and investigation of singlet oxygen production efficiency of photosensitizers based on meso-phenyl-2,5-thienylene linked porphyrin oligomers and polymers
(Royal Society of Chemistry, 2015)Three new Zn(ii)-, oligo- and poly(2,5-thienylene)-linked porphyrins, bearing multiple triethylene glycol (TEG) groups, on all meso aryl positions were synthesized via Stille and Suzuki coupling reactions and their ...
