Browsing by Keywords "Peptide nanofibers"
Now showing items 1-12 of 12
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Affinity of glycopeptide nanofibers to growth factors and their effects on cells
(Bilkent University, 2017-09)The development of scaffolds for growth factor delivery is a promising approach for tissue regeneration applications due to their crucial roles during regeneration. Growth factor secretion and interactions with glycosaminoglycans ... -
Angiogenic peptide nanofibers repair cardiac tissue defect after myocardial infarction
(Acta Materialia Inc, 2017)Myocardial infarction remains one of the top leading causes of death in the world and the damage sustained in the heart eventually develops into heart failure. Limited conventional treatment options due to the inability ... -
Development of peptide based materials as a synthetic scaffold to mimic extracellular matrix
(Bilkent University, 2017-07)Biomaterials obtained through self-assembling process of peptide amphiphile (PA) molecules provide great potential to introduce new therapeutic approaches in regenerative medicine through mimicking the natural environments ... -
Development of peptide nanomaterials for neural regeneration
(Bilkent University, 2015-05)Nervous system consists of a dense network of cells and their connections and exhibits a high level of complexity. This complexity arises from the high variety of cell types with very specific functions, the high number ... -
Extracellular matrix mimetic peptide scaffolds for neural stem cell culture and differentiation
(Humana Press, 2014)Self-assembled peptide nanofibers form three-dimensional networks that are quite similar to fibrous extracellular matrix (ECM) in their physical structure. By incorporating short peptide sequences derived from ECM proteins, ... -
Improving pancreatic islet in vitro functionality and transplantation efficiency by using heparin mimetic peptide nanofiber gels
(Elsevier, 2015)Pancreatic islet transplantation is a promising treatment for type 1 diabetes. However, viability and functionality of the islets after transplantation are limited due to loss of integrity and destruction of blood vessel ... -
Investigating the effects of bioactive peptide nanofibers on the growth and differentiation behaviour of nervous system cells
(Bilkent University, 2017-07)Peripheral nerve regeneration is a tightly regulated process that entails the degeneration, proliferation, alignment and remyelination of Schwann cells. Tuning the bioactivity is important to support all of these processes ... -
Investigation of the effects of bioactive peptide nanofibers on acute muscle injury regeneration
(Bilkent University, 2016-10)Skeletal muscle constitutes a large part of the human body. It is a hierarchically organized heterogeneous tissue and is composed of muscle fiber bundles, muscle fibers, myofibrils and myofilaments. Since muscle cells are ... -
Peptide nanofiber scaffolds for multipotent stromal cell culturing
(Humana Press Inc., 2013)Self-assembled peptide nanofibers are versatile materials providing suitable platforms for regenerative medicine applications. This chapter describes the use of peptide nanofibers as extracellular matrix mimetic scaffolds ... -
Peptide nanofibers for controlled growth factor release
(Future Science Ltd., 2013)[No abstract available] -
Peripheral nerve regeneration by synthetic peptide nanofibers
(Bilkent University, 2016-09)The peripheral nervous system (PNS) has a complex structure that consists of high numbers of nerve cells and communication networks between the central nervous system and the body parts. Unlike the central nervous system, ... -
Programming microenvironmental signals with bioactive peptide amphiphiles for skeletal and cardiac myogenesis
(Bilkent University, 2014)The extracellular matrix (ECM) is crucial for the coordination and regulation of various cellular processes, including cell adhesion, recruitment, differentiation and death. ECM components structurally support tissue ...
