Browsing by Keywords "Peptide nanofiber"
Now showing items 1-9 of 9
-
Bioactive glycopeptide nanofibers for tissue regeneration applications
(Bilkent University, 2016-05)Natural extracellular matrix (ECM) is rich in glycopeptides and glycosaminoglycans, which function in controlling cellular processes. In this thesis, glycopeptide molecules that mimic natural glycopeptides and glycosaminoglycans ... -
Biotin functionalized self‐assembled peptide nanofiber as an adjuvant for immunomodulatory response
(Wiley-VCH Verlag, 2020-12)Biotinylated peptide amphiphile (Biotin‐PA) nanofibers, are designed as a noncovalent binding location for antigens, which are adjuvants to enhance, accelerate, and prolong the immune response triggered by antigens. ... -
Collagen peptide presenting nanofibrous scaffold for intervertebral disc regeneration
(American Chemical Society, 2019)Lower back pain (LBP) is a prevalent spinal symptom at the lumbar region of the spine, which severely effects quality of life and constitutes the number one cause of occupational disability. Degeneration of the intervertebral ... -
Design and development of ecm-inspired peptidebased nanostructures for bioengineering and biomedicine
(Bilkent University, 2017-08)Advances in understanding of cell-matrix interactions and the regulation of cellular behaviors through nanobiotechnological tools have presented new perspectives for regenerative medicine. Peptide amphiphiles have been ... -
Development of bioactive peptide nanofibers for intervertebral disc regeneration
(Bilkent University, 2017-08)Lower back pain (LBP) and neck problems are the most common orthopedic diseases worldwide, and the main reason behind LBP is intervertebral disc degeneration (IVDD). Therefore, specialized therapeutic applications to induce ... -
Heparin mimetic peptide nanofiber gel promotes regeneration of full thickness burn injury
(Elsevier Ltd, 2017)Burn injuries are one of the most common types of trauma worldwide, and their unique physiology requires the development of specialized therapeutic materials for their treatment. Here, we report the use of synthetic, ... -
Laminin mimetic peptide nanofibers regenerate acute muscle defect
(Acta Materialia Inc, 2017)Skeletal muscle cells are terminally differentiated and require the activation of muscle progenitor (satellite) cells for their regeneration. There is a clinical need for faster and more efficient treatment methods for ... -
Multivalent presentation of cationic peptides on supramolecular nanofibers for antimicrobial activity
(American Chemical Society, 2017)Noncovalent and electrostatic interactions facilitate the formation of complex networks through molecular self-assembly in biomolecules such as proteins and glycosaminoglycans. Self-assembling peptide amphiphiles (PA) are ... -
Self-assembly of peptide nanofibers and their mechanical properties
(Bilkent University, 2012)Peptide nanofibers have been drawing attention because of their versatile, tailorable and functional properties in various research areas. The self-assembly mechanism of peptides and peptide amphiphile molecules is ...
