Browsing by Keywords "Nanofiber"
Now showing items 1-20 of 65
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Angiogenic heparin-mimetic peptide nanofiber gel improves regenerative healing of acute wounds
(American Chemical Society, 2017)Wound repair in adult mammals typically ends with the formation of a scar, which prevents full restoration of the function of the healthy tissue, although most of the wounded skin heals. Rapid and functional recovery of ... -
Angiogenic peptide nanofibers improve wound healing in STZ-induced diabetic rats
(American Chemical Society, 2016-06)Low expressions of angiogenic growth factors delay the healing of diabetic wounds by interfering with the process of blood vessel formation. Heparin mimetic peptide nanofibers can bind to and enhance production and activity ... -
Angiogenic peptide nanofibers repair cardiac tissue defect after myocardial infarction
(Acta Materialia Inc, 2017)Myocardial infarction remains one of the top leading causes of death in the world and the damage sustained in the heart eventually develops into heart failure. Limited conventional treatment options due to the inability ... -
Antibacterial electrospun nanofibers from triclosan/cyclodextrin inclusion complexes
(Elsevier, 2014)The electrospinning of nanofibers (NF) from cyclodextrin inclusion complexes (CD-IC) with an antibacterial agent (triclosan) was achieved without using any carrier polymeric matrix. Polymer-free triclosan/CD-IC NF were ... -
Antibacterial electrospun zein nanofibrous web encapsulating thymol/cyclodextrin-inclusion complex for food packaging
(Elsevier, 2017-10)Thymol (THY)/γ-Cyclodextrin(γ-CD) inclusion complex (IC) encapsulated electrospun zein nanofibrous webs (zein-THY/γ-CD-IC-NF) were fabricated as a food packaging material. The formation of THY/γ-CD-IC (1:1 and 2:1) was ... -
Antioxidant activity and photostability of α-tocopherol/β-cyclodextrin inclusion complex encapsulated electrospun polycaprolactone nanofibers
(Elsevier, 2016-06)Cyclodextrin inclusion complexes (CD-ICs) can be encapsulated into electrospun nanofibers in order to achieve delivery systems having high surface area and highly porous nanofibrous structures. In this study, a well-known ... -
Bacteria encapsulated electrospun nanofibrous webs for remediation of methylene blue dye in water
(Elsevier, 2017-04)In this study, preparation and application of novel biocomposite materials that were produced by encapsulation of bacterial cells within electrospun nanofibrous webs are described. A commercial strain of Pseudomonas ... -
Bacteria immobilized electrospun polycaprolactone and polylactic acid fibrous webs for remediation of textile dyes in water
(Elsevier, 2017-10)In this study, preparation and application of novel biocomposite materials for textile dye removal which are produced by immobilization of specific bacteria onto electrospun nanofibrous webs are presented. A textile dye ... -
Bioactive supramolecular peptide nanofibers for regenerative medicine
(Wiley, 2014)Recent advances in understanding of cell-matrix interactions and the role of the extracellular matrix (ECM) in regulation of cellular behavior have created new perspectives for regenerative medicine. Supramolecular peptide ... -
Biocompatible supramolecular catalytic one-dimensional nanofibers for efficient labeling of live cells
(American Chemical Society, 2015)Understanding complex cellular functions requires study and tracking of biomolecules such as proteins, glycans, and lipids in their natural environment. Herein, we report the first supramolecular nanocatalyst for bioorthogonal ... -
Biotinylated peptide nanofibers for modulating the immune response
(Bilkent University, 2016-06)Despite the fact that vaccination eradicates many diseases, a broad variety of disorders cannot be treated using current vaccine development methods. In addition, it is difficult to rapidly develop new vaccines following ... -
Cellular internalization of therapeutic oligonucleotides by peptide amphiphile nanofibers and nanospheres
(American Chemical Society, 2016-04)Oligonucleotides are promising drug candidates due to the exceptionally high specificity they exhibit toward their target DNA and RNA sequences. However, their poor pharmacokinetic and pharmacodynamic properties, in ... -
Chondrogenic differentiation of mesenchymal stem cells on glycosaminoglycan-mimetic peptide nanofibers
(American Chemical Society, 2016)Glycosaminoglycans (GAGs) are important extracellular matrix components of cartilage tissue and provide biological signals to stem cells and chondrocytes for development and functional regeneration of cartilage. Among their ... -
CO2 laser machining for microfluidics mold fabrication from PMMA with applications on viscoelastic focusing, electrospun nanofiber production, and droplet generation
(Elsevier, 2021-03-26)In this study, a new method for the fabrication of polydimethylsiloxane (PDMS) microchannels through the replication of plexiglass molds was developed. A plexiglass slab is machined with CO2 laser in the raster mode to ... -
Colon targeted delivery of niclosamide from β-cyclodextrin inclusion complex incorporated electrospun Eudragit® L100 nanofibers
(Elsevier BV, 2021-01)Electrospun nanofibers incorporated with inclusion complex (IC) of niclosamide (NIC) and hydroxypropyl-beta-cyclodextrin (HPβCD) (NIC-HPβCD-IC) was produced from pH-responsive polymer (Eudragit® L100, EUD), which disintegrates ... -
Cyclodextrin functionalized poly(methyl methacrylate) (PMMA) electrospun nanofibers for organic vapors waste treatment
(Elsevier BV, 2010)Poly(methyl methacrylate) (PMMA) nanofibers containing the inclusion complex forming betacyclodextrin (_-CD) were successfully produced by means of electrospinning in order to develop functional nanofibrous webs for ... -
Design and fabrication of auxetic PCL nanofiber membranes for biomedical applications
(Elsevier, 2017-12)The main objective of this study was to fabricate poly (ε-caprolactone) (PCL)-based auxetic nanofiber membranes and characterize them for their mechanical and physicochemical properties. As a first step, the PCL nanofibers ... -
Development of biointegrated electrospun nanofibers for environmental applications
(Bilkent University, 2016-08)Electrospinning is an easy and economical production technique to produce nanofiber/nanofibrous webs from different polymers, polymer mixtures, inorganic materials, supramolecular structures and composite materials. These ... -
Development of photoanodes for performance enhanced dye sensitized solar cells
(Bilkent University, 2015-08)With a raising demand for clean and renewable energy sources in recent decades, dye sensitized solar cell (DSSC), as an efficient and low-cost solar cell technology, have attracted considerable attention and several efforts ... -
Drug delivery system based on cyclodextrin-naproxen inclusion complex incorporated in electrospun polycaprolactone nanofibers
(Elsevier, 2014)In this study, we select naproxen (NAP) as a reference drug and electrospun poly (e-caprolactone) (PCL) nanofibers as a fibrous matrix for our drug-delivery system. NAP was complexed with beta-cyclodextrin (βCD) to form ...