Now showing items 1-20 of 91

    • 15-Lipoxygenase-1 re-expression in colorectal cancer alters endothelial cell features through enhanced expression of TSP-1 and ICAM-1 

      Tunçer, S.; Keşküş, A. G.; Çolakoğlu, M.; Çimen, I.; Yener, C.; Konu, Ö.; Banerjee, S. (Elsevier, 2017-11)
      15-lipoxygenase-1 (15-LOX-1) oxygenates linoleic acid to 13(S)-hydroxyoctadecadienoic acid (HODE). The enzyme is widely suppressed in different cancers and its re-expression has tumor suppressive effects. 15-LOX-1 has been ...
    • Adjuvant autologous melanoma vaccine for macroscopic stage III disease: survival, biomarkers, and improved response to CTLA-4 blockade 

      Lotem, M.; Merims, S.; Frank, S.; Hamburger, T.; Nissan, A.; Kadouri, L.; Cohen, J.; Straussman, R.; Eisenberg, G.; Frankenburg, S.; Carmon, E.; Alaiyan, B.; Shneibaum, S.; Ayyildiz, Z. O.; Isbilen, M.; Senses, K. M.; Ron, I.; Steinberg, H.; Smith, Y.; Shiloni, E.; Gure, A. O.; Peretz, T. (Hindawi Limited, 2016)
      Background. There is not yet an agreed adjuvant treatment for melanoma patients with American Joint Committee on Cancer stages III B and C. We report administration of an autologous melanoma vaccine to prevent disease ...
    • Angiogenic heparin-mimetic peptide nanofiber gel improves regenerative healing of acute wounds 

      Uzunalli, G.; Mammadov R.; Yesildal, F.; Alhan, D.; Ozturk, S.; Ozgurtas, T.; Guler, M. O.; Tekinay, A. B. (American Chemical Society, 2017)
      Wound repair in adult mammals typically ends with the formation of a scar, which prevents full restoration of the function of the healthy tissue, although most of the wounded skin heals. Rapid and functional recovery of ...
    • Angiogenic peptide nanofibers improve wound healing in STZ-induced diabetic rats 

      Senturk, B.; Mercan, S.; Delibasi, T.; Guler, M. O.; Tekinay, A. B. (American Chemical Society, 2016-06)
      Low expressions of angiogenic growth factors delay the healing of diabetic wounds by interfering with the process of blood vessel formation. Heparin mimetic peptide nanofibers can bind to and enhance production and activity ...
    • Angiogenic peptide nanofibers repair cardiac tissue defect after myocardial infarction 

      Rufaihah, A. J.; Yasa, I. C.; Ramanujam, V. S.; Arularasu, S. C.; Kofidis, T.; Guler, M. O.; Tekinay, A. B. (Acta Materialia Inc, 2017)
      Myocardial infarction remains one of the top leading causes of death in the world and the damage sustained in the heart eventually develops into heart failure. Limited conventional treatment options due to the inability ...
    • Application of the RIMARC algorithm to a large data set of action potentials and clinical parameters for risk prediction of atrial fibrillation 

      Ravens, U.; Katircioglu-Öztürk, D.; Wettwer, E.; Christ, T.; Dobrev, D.; Voigt, N.; Poulet, C.; Loose, S.; Simon, J.; Stein, A.; Matschke, K.; Knaut, M.; Oto, E.; Oto, A.; Güvenir, H. A. (Springer, 2015)
      Ex vivo recorded action potentials (APs) in human right atrial tissue from patients in sinus rhythm (SR) or atrial fibrillation (AF) display a characteristic spike-and-dome or triangular shape, respectively, but variability ...
    • Assessment of diagnostic enzyme-linked immunosorbent assay kit and serological markers in human brucellosis 

      Cakan G.; Bezirci F.B.; Kacka, A.; Cesur, S.; Aksaray, S.; Tezeren, D.; Saka, D.; Ahmed, K. (2008)
      This study was performed to evaluate commercial brucella immunoglobulin G and M-enzymelinked immunosorbent assay (IgG and IgM ELISA) kits for the diagnosis of human brucellosis and to suggest a candidate prognostic marker ...
    • Beyond the 'East-West' dichotomy: Global variation in cultural models of selfhood 

      Vignoles, V. L.; Owe, E.; Becker, M.; Smith, P. B.; Easterbrook, M. J.; Brown, R.; González, R.; Didier, N.; Carrasco, D.; Cadena, M. P.; Lay, S.; Schwartz, S. J.; Rosiers, S. E. D.; Villamar, J. A.; Gavreliuc, A.; Zinkeng, M.; Kreuzbauer, R.; Baguma, P.; Martin, M.; Tatarko, A.; Herman, G.; de Sauvage, I.; Courtois, M.; Gardarsdóttir, R. B.; Harb, C.; Gallo, I. S.; Gil, P. P.; Clemares, R. L.; Campara, G.; Nizharadze, G.; Macapagal, M. E. J.; Jalal, B.; Bourguignon, D.; Zhang, J.; Lv, S.; Chybicka, A.; Yuki, M.; Zhang X.; Espinosa, A.; Valk, A.; Abuhamdeh, S.; Amponsah, B.; Özgen E.; Guner, E. Ü.; Yamakoglu, N.; Chobthamkit, P.; Pyszczynski, T.; Kesebir, P.; Trujillo, E. V.; Balanta, P.; Ayala, B. C.; Koller, S. H.; Jaafar, J. L.; Gausel, N.; Fischer, R.; Milfont, T. L.; Kusdil, E.; Çağlar, S.; Aldhafri, S.; Ferreira, M. C.; Mekonnen, K. H.; Wang, Q.; Fülöp, M.; Torres, A.; Camino, L.; Lemos, F. C. S.; Fritsche, I.; Möller, B.; Regalia, C.; Manzi, C.; Brambilla, M.; Bond, M. H. (American Psychological Association Inc., 2016)
      Markus and Kitayama's (1991) theory of independent and interdependent self-construals had a major influence on social, personality, and developmental psychology by highlighting the role of culture in psychological processes. ...
    • BRAPH: A graph theory software for the analysis of brain connectivity 

      Mijalkov, M.; Kakaei, E.; Pereira, J. B.; Westman, E.; Volpe, G. (Public Library of Science, 2017)
      The brain is a large-scale complex network whose workings rely on the interaction between its various regions. In the past few years, the organization of the human brain network has been studied extensively using concepts ...
    • Characterization of a novel zebrafish (Danio rerio) gene, wdr81, associated with cerebellar ataxia, mental retardation and dysequilibrium syndrome (CAMRQ) 

      Doldur-Balli, F.; Ozel, M. N.; Gulsuner, S.; Tekinay, A. B.; Ozcelik, T.; Konu, O.; Adams, M. M. (BioMed Central Ltd., 2015)
      Background: WDR81 (WD repeat-containing protein 81) is associated with cerebellar ataxia, mental retardation and disequilibrium syndrome (CAMRQ2, [MIM 610185]). Human and mouse studies suggest that it might be a gene of ...
    • Choroid Plexus Papillomas in two Siblings: Case Report 

      Okay O.; Daglioglu, E.; Yakicier, C.; Uren, D.; Dalgic, A.; Ergungor F. (2009)
      Choroid plexus papilloma (CPP) is a rare, benign epithelial brain tumor of the nervous system seen particularly in infants. Familial cases are extremely uncommon. Some other form of malignant tumors was noted in the relatives ...
    • Coagulation factor V gene mutation increases the risk of venous thrombosis in Behcet's disease 

      Gül, A.; Özbek, U.; Öztürk, C.; Inanç, M.; Koniçe, M.; Özçelik, T. (Oxford University Press, 1996)
      We investigated the prevalence of the coagulation factor V gene G1691A mutation in 64 patients with Behcet's disease (BD) and in 107 apparently healthy individuals. The mutation was present in the heterozygous state in ...
    • Cognitive and emotional representations of terror attacks: a cross-cultural exploration 

      Shiloh, S.; Güvenç, G.; Önkal D. (Wiley-Blackwell Publishing, 2007)
      A questionnaire measuring cognitive and affective representations of terror risk was developed and tested in Turkey and Israel. Participants in the study were university students from the two countries (n = 351). Four ...
    • Colon cancer associated transcript-1 (CCAT1) expression in adenocarcinoma of the stomach 

      Mizrahi, I.; Mazeh, H.; Grinbaum, R.; Beglaibter, N.; Wilschanski, M.; Pavlov, V.; Adileh, M.; Stojadinovic, A.; Avital, I.; Gure, A. O.; Halle, D.; Nissan, A. (Ivyspring International Publisher, 2015)
      Background: Long non-coding RNAs (lncRNAs) have been shown to have functional roles in cancer biology and are dys-regulated in many tumors. Colon Cancer Associated Transcript -1 (CCAT1) is a lncRNA, previously shown to be ...
    • A combined ULBP2 and SEMA5A expression signature as a prognostic and predictive biomarker for colon cancer 

      Demirkol, S.; Gomceli, I.; Isbilen, M.; Dayanc, B. E.; Tez, M.; Bostanci, E. B.; Turhan, N.; Akoglu, M.; Ozyerli, E.; Durdu, S.; Konu, O.; Nissan, A.; Gonen, M.; Gure, A. O. (Ivyspring International Publisher, 2017)
      Background: Prognostic biomarkers for cancer have the power to change the course of disease if they add value beyond known prognostic factors, if they can help shape treatment protocols, and if they are reliable. The aim ...
    • Comparison of original EuroSCORE, EuroSCORE II and STS risk models in a Turkish cardiac surgical cohort 

      Kunt, A.G.; Kurtcephe, M.; Hidiroglu, M.; Cetin L.; Kucuker, A.; Bakuy V.; Ruchan Akar, A.; Sener, E. (2013)
      OBJECTIVESThe aim of this study was to compare additive and logistic European System for Cardiac Operative Risk Evaluation (EuroSCORE), EuroSCORE II and the Society of Thoracic Surgeons (STS) models in calculating mortality ...
    • Context-dependent lightness affects perceived contrast 

      Pamir, Z.; Boyaci, H. (Elsevier Ltd, 2016)
      Perceived contrast of a grating varies with its background (or mean) luminance: of the two gratings with the same photometric contrast the one on higher luminance background appears to have higher contrast. Does perceived ...
    • Copy number variation of individual cattle genomes using next-generation sequencing 

      Bickhart, D.M.; Hou, Y.; Schroeder, S.G.; Alkan C.; Cardone, M.F.; Matukumalli L.K.; Song J.; Schnabel, R.D.; Ventura M.; Taylor J.F.; Garcia J.F.; Van Tassell, C.P.; Sonstegard, T.S.; Eichler, E. E.; Liu G.E. (2012)
      Copy number variations (CNVs) affect a wide range of phenotypic traits; however, CNVs in or near segmental duplication regions are often intractable. Using a read depth approach based on next-generation sequencing, we ...
    • Cultural Bases for Self-Evaluation: Seeing Oneself Positively in Different Cultural Contexts 

      Becker, M.; Vignoles, V. L.; Owe, E.; Easterbrook, M. J.; Brown, R.; Smith, P. B.; Bond, M. H.; Regalia, C.; Manzi, C.; Brambilla, M.; Aldhafri, S.; González, R.; Carrasco, D.; Cadena, M. P.; Lay, S.; Gallo I. S.; Torres, A.; Camino L.; Özgen E.; Güner, Ü.E.; Yamakoğlu, N.; Lemos, F. C. S.; Trujillo, E. V.; Balanta, P.; Macapagal, M. E. J.; Ferreira, M. C.; Herman, G.; de Sauvage, I.; Bourguignon, D.; Wang, Q.; Fülöp, M.; Harb, C.; Chybicka, A.; Mekonnen, K. H.; Martin, M.; Nizharadze, G.; Gavreliuc, A.; Buitendach J.; Valk, A.; Koller, S. H. (SAGE Publications Inc.SAGE, 2014)
      Several theories propose that self-esteem, or positive self-regard, results from fulfilling the value priorities of one's surrounding culture. Yet, surprisingly little evidence exists for this assertion, and theories differ ...
    • Data mining experiments on the Angiotensin II-Antagonist in Paroxysmal Atrial Fibrillation (ANTIPAF-AFNET 2) trial: ‘exposing the invisible’ 

      Okutucu, S.; Katircioglu-Öztürk, D.; Oto, E.; Güvenir, H. A.; Karaagaoglu, E.; Oto, A.; Meinertz, T.; Goette, A. (Oxford University Press, 2016)
      Aims: The aims of this study include (i) pursuing data-mining experiments on the Angiotensin II-Antagonist in Paroxysmal Atrial Fibrillation (ANTIPAF-AFNET 2) trial dataset containing atrial fibrillation (AF) burden scores ...