Browsing by Keywords "Macrophages"
Now showing items 1-5 of 5
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Adenosine regulation of danger signaling
(Bilkent University, 2017-08)Metabolic and immune related activities converge as main triggers of adenosine accumulation in extracellular space. Adenosine by engaging adenosine A2A and A2B receptors strongly suppresses innate and adaptive immune ... -
Jnk1 deficiency in hematopoietic cells suppresses macrophage apoptosis and increases atherosclerosis in low-density lipoprotein receptor null mice
(Lippincott Williams and Wilkins, 2016)Objective - The c-Jun NH 2 -terminal kinases (JNK) are regulated by a wide variety of cellular stresses and have been implicated in apoptotic signaling. Macrophages express 2 JNK isoforms, JNK1 and JNK2, which may have ... -
Macrophage Mal1 deficiency suppresses atherosclerosis in low-density lipoprotein receptor-null mice by activating peroxisome proliferator-activated receptor-g-regulated genes
(Lippincott Williams & Wilkins, 2011)Objective-The adipocyte/macrophage fatty acid-binding proteins aP2 (FABP4) and Mal1 (FABP5) are intracellular lipid chaperones that modulate systemic glucose metabolism, insulin sensitivity, and atherosclerosis. Combined ... -
One-Step Fabrication of Biocompatible Multifaceted Nanocomposite Gels and Nanolayers
(American Chemical Society, 2017)Nanocomposite gels are a fascinating class of polymeric materials with an integrative assembly of organic molecules and organic/inorganic nanoparticles, offering a unique hybrid network with synergistic properties. The ... -
Platelet-derived microparticles differentially regulate macrophage polarization
(Bilkent University, 2016-09)Platelet-derived microparticles (PMPs) shed from platelets upon activation and constitute almost 90% of the circulating microparticles. Due to their versatile cargo, PMPs were associated with the generation of immunosuppressive ...
