Browsing by Keywords "Laminin"
Now showing items 1-6 of 6
-
A hybrid nanofiber matrix to control the survival and maturation of brain neurons
(Elsevier BV, 2012)Scaffold design plays a crucial role in developing graft-based regenerative strategies, especially when intended to be used in a highly ordered nerve tissue. Here we describe a hybrid matrix approach, which combines the ... -
Investigation of spontaneous differentiation of neural stem cells on synthetic scaffolds
(Bilkent University, 2017-08)Despite the increasing incidents of brain injuries and neurodegenerative diseases, a definitive clinical therapy for these conditions has not been found yet. Nervous system injuries result in loss of neural cells, causing ... -
Investigation of the effects of bioactive peptide nanofibers on acute muscle injury regeneration
(Bilkent University, 2016-10)Skeletal muscle constitutes a large part of the human body. It is a hierarchically organized heterogeneous tissue and is composed of muscle fiber bundles, muscle fibers, myofibrils and myofilaments. Since muscle cells are ... -
Laminin mimetic peptide nanofibers regenerate acute muscle defect
(Acta Materialia Inc, 2017)Skeletal muscle cells are terminally differentiated and require the activation of muscle progenitor (satellite) cells for their regeneration. There is a clinical need for faster and more efficient treatment methods for ... -
Neuroactive peptide nanofibers for regeneration of spinal cord after injury
(Wiley-VCH Verlag GmbH & Co. KGaA, 2020-10-11)The highly complex nature of spinal cord injuries (SCIs) requires design of novel biomaterials that can stimulate cellular regeneration and functional recovery. Promising SCI treatments use biomaterial scaffolds, which ... -
Three-Dimensional Laminin Mimetic Peptide Nanofiber Gels for In Vitro Neural Differentiation
(Wiley-VCH Verlag, 2017)The extracellular matrix (ECM) provides biochemical signals and structural support for cells, and its functional imitation is a fundamental aspect of biomaterial design for regenerative medicine applications. The stimulation ...
