Browsing by Keywords "Immune activation"

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Circulating LL37 targets plasma extracellular vesicles to immune cells and intensifies Behçet's disease severity

Kahraman, T.; Gucluler, G.; Simsek, I.; Yagci, F. C.; Yildirim, M.; Ozen, C.; Dinc, A.; Gursel, M.; Ikromzoda, L.; Sutlu, T.; Gay, S.; Gursel, I. (Taylor and Francis, 2017-02)

Behçet's disease (BD) activity is characterised by sustained, over-exuberant immune activation, yet the underlying mechanisms leading to active BD state are poorly defined. Herein, we show that the human cathelicidin derived ...
A self assembled nanofibrous structure as a novel vaccine adjuvant

Demircan, Muhammed Burak (Bilkent University, 2017-02)

Vaccination is the most effective and cost-efficient way of protection against the major infectious diseases but ideal vaccine formulation has not been found. Recent vaccine systems are mainly composed of two major substitutes ...