Browsing by Keywords "Glycosaminoglycans"
Now showing items 1-8 of 8
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Affinity of glycopeptide nanofibers to growth factors and their effects on cells
(Bilkent University, 2017-09)The development of scaffolds for growth factor delivery is a promising approach for tissue regeneration applications due to their crucial roles during regeneration. Growth factor secretion and interactions with glycosaminoglycans ... -
Biomimetic self-assembled peptide nanofibers for bone regeneration
(Bilkent University, 2012)Self-assembled peptide nanofibers are exploited in regenerative medicine applications due to their versatile, biofunctional and extracellular-matrixresembling structures. These properties provide peptide nanofibers ... -
Development and characterization of peptide nanofibers for cartilage regeneration
(Bilkent University, 2015-09)Articular cartilage is a tissue that is continuously exposed to cyclical compressive stresses, but exhibits no capacity for self-healing following trauma. Cartilage has a dense extracellular matrix that is sparsely ... -
Diabetic wound regeneration using heparin-mimetic peptide amphiphile gel in db/db mice
(Royal Society of Chemistry, 2017)There is an urgent need for more efficient treatment of chronic wounds in diabetic patients especially with a high risk of leg amputation. Biomaterials capable of presenting extracellular matrix-mimetic signals may assist ... -
Effect of double growth factor release on cartilage tissue engineering
(2013)The effects of double release of insulin-like growth factor I (IGF-I) and growth factor β1 (TGF-β1) from nanoparticles on the growth of bone marrow mesenchymal stem cells and their differentiation into cartilage cells were ... -
Sciatic nerve regeneration induced by glycosaminoglycan and laminin mimetic peptide nanofiber gels
(Royal Society of Chemistry, 2016)In the USA, 20 million patients suffer from neuropathy caused by peripheral nerve injuries, which costs approximately 150 billion annually. For longer nerve gaps and multiple injury sites, it is essential to use nerve ... -
Small functional groups presented on peptide nanofibers for determining fate of rat mesenchymal stem cells
(Bilkent University, 2014)Glycosaminoglycans (GAGs) are negatively-charged, unbranched polysaccharides that play important roles in various biological processes and are vital for the regeneration of damaged tissues. Like other natural extracellular ... -
Three dimensional glycosaminoglycan mimetic peptide amphiphile hydrogels for regenerative medicine applications
(Bilkent University, 2015-05)Defects and impairments of tissues or organs affect millions of people, resulting in considerable losses in workforce and life quality. The treatment of major tissue injuries requires the development of advanced medical ...
