Now showing items 1-20 of 20

    • Can you really anonymize the donors of genomic data in today’s digital world? 

      Alser, M.; Almadhoun, N.; Nouri, A.; Alkan C.; Ayday, E. (Springer Verlag, 2016)
      The rapid progress in genome sequencing technologies leads to availability of high amounts of genomic data. Accelerating the pace of biomedical breakthroughs and discoveries necessitates not only collecting millions of ...
    • Cryptographic solutions for genomic privacy 

      Ayday, E. (Springer Verlag, 2016)
      With the help of rapidly developing technology, DNA sequencing is becoming less expensive. As a consequence, the research in genomics has gained speed in paving the way to personalized (genomic) medicine, and geneticists ...
    • Data and model driven hybrid approach to activity scoring of cyclic pathways 

      Işik, Z.; Atalay V.; Aykanat, C.; Çetin-Atalay, R. (2010)
      Analysis of large scale -omics data based on a single tool remains inefficient to reveal molecular basis of cellular events. Therefore, data integration from multiple heterogeneous sources is highly desirable and required. ...
    • Differential privacy with bounded priors: Reconciling utility and privacy in genome-wide association studies 

      Tramèr F.; Huang, Z.; Hubaux J.-P.; Ayday, E. (Association for Computing Machinery, 2015)
      Differential privacy (DP) has become widely accepted as a rigorous definition of data privacy, with stronger privacy guarantees than traditional statistical methods. However, recent studies have shown that for reasonable ...
    • Environmental effect and genetic influence: A regional cancer predisposition survey in the Zonguldak region of Northwest Turkey 

      Kadir, S.; Önen-Hall, A. P.; Aydin, S. N.; Yakicier, C.; Akarsu, N.; Tuncer, M. (Springer-Verlag, 2008)
      The Cretaceous-Eocene volcano-sedimentary units of the Zonguldak region of the western Black Sea consist of subalkaline andesite and tuff, and sandstone dominated by smectite, kaolinite, accessory chlorite, illite, mordenite, ...
    • GenoGuard: protecting genomic data against brute-force attacks 

      Huang Z.; Ayday, E.; Fellay J.; Hubaux, Jean-Pierre; Juels, A. (Institute of Electrical and Electronics Engineers Inc., 2015)
      Secure storage of genomic data is of great and increasing importance. The scientific community's improving ability to interpret individuals' genetic materials and the growing size of genetic database populations have been ...
    • Genomic landscape of the Greater Middle East 

      Özçelik, T.; Onat, O. E. (Nature Publishing Group, 2016-09)
      Study of the Greater Middle East (GME), home to approximately 10% of the world's population, has made invaluable contributions to the characterization of rare genetic disease, especially recessive conditions arising from ...
    • HER2 and proliferation of wound-induced breast carcinoma 

      Tez, M.; Göçmen, E.; Özçelik, T. (The Lancet Publishing, 2003-11-01)
    • Inference attacks against kin genomic privacy 

      Ayday, E.; Humbert M. (Institute of Electrical and Electronics Engineers Inc., 2017)
      Genomic data poses serious interdependent risks: your data might also leak information about your family members' data. Methods attackers use to infer genomic information, as well as recent proposals for enhancing genomic ...
    • Inter-varietal structural variation in grapevine genomes 

      Cardone, M. F.; D'Addabbo, P.; Alkan C.; Bergamini, C.; Catacchio, C. R.; Anaclerio, F.; Chiatante, G.; Marra, A.; Giannuzzi, G.; Perniola, R.; Ventura M.; Antonacci, D. (Wiley-Blackwell Publishing Ltd., 2016)
      Grapevine (Vitis vinifera L.) is one of the world's most important crop plants, which is of large economic value for fruit and wine production. There is much interest in identifying genomic variations and their functional ...
    • Mammalian telomeric DNA suppresses endotoxin-induced uveitis 

      Yagci, F. C.; Aslan, O.; Gursel, M.; Tincer, G.; Özdamar, Y.; Karatepe, K.; Akcali, K. C.; Gursel, I. (American Society for Biochemistry and Molecular Biology Inc., 2010)
      Telomeric regions of mammalian chromosomes contain suppressive TTAGGG motifs that inhibit several proinflammatory and Th1-biased immune responses. Synthetic oligodeoxynucleotides (ODN) expressing suppressive motifs can ...
    • On non-cooperative genomic privacy 

      Humbert, M.; Ayday, E.; Hubaux J.-P.; Telenti, A. (Springer Verlag, 2015)
      Over the last few years, the vast progress in genome sequencing has highly increased the availability of genomic data. Today, individuals can obtain their digital genomic sequences at reasonable prices from many online ...
    • Privacy and security in the genomic era 

      Ayday, E.; Hubaux, Jean-Pierre (Association for Computing Machinery, 2016)
      With the help of rapidly developing technology, DNA sequencing is becoming less expensive. As a consequence, the research in genomics has gained speed in paving the way to personalized (genomic) medicine, and geneticists ...
    • Privacy in the genomic era 

      Naveed, M.; Ayday, E.; Clayton, E.W.; Fellay J.; Gunter, C.A.; Hubaux J.-P.; Malin, B.A.; Wang, X. (Association for Computing Machinery, 2015)
      Genome sequencing technology has advanced at a rapid pace and it is now possible to generate highlydetailed genotypes inexpensively. The collection and analysis of such data has the potential to support various applications, ...
    • Privacy threats and practical solutions for genetic risk tests 

      Barman, L.; Elgraini, M.-T.; Raisaro, J. L.; Hubaux, J. -P.; Ayday, E. (Institute of Electrical and Electronics Engineers Inc., 2015)
      Recently, several solutions have been proposed to address the complex challenge of protecting individuals' genetic data during personalized medicine tests. In this short paper, we analyze different privacy threats and ...
    • Production and structural characterization of biosurfactant produced by newly isolated staphylococcus xylosus STF1 from petroleum contaminated soil 

      Keskin, N. O. S.; Han, D.; Ozkan A.D.; Angun, P.; Umu, O. C. O.; Tekinay, T. (Elsevier BV, 2015)
      Petroleum-contaminated soil was used to isolate and characterize biosurfactant producing bacteria. The strain could produce higher amount of biosurfactant in medium supplemented with motor oil as sole source of carbon and ...
    • Quantifying genomic privacy via inference attack with high-order SNV correlations 

      Samani, S. S.; Huang, Z.; Ayday, E.; Elliot, M.; Fellay, J.; Hubaux, J.-P.; Kutalik, Z. (Institute of Electrical and Electronics Engineers Inc., 2015)
      As genomic data becomes widely used, the problem of genomic data privacy becomes a hot interdisciplinary research topic among geneticists, bioinformaticians and security and privacy experts. Practical attacks have been ...
    • A secant condition for cyclic systems with time delays and its application to Gene Regulatory Networks 

      Ahsen, M.E.; Özbay H.; Niculescu, S.-I. (IFAC Secretariat, 2015)
      A stability condition is derived for cyclic systems with time delayed negative feedback. The result is an extension of the so-called secant condition, which is originally developed for systems without time delays. This ...
    • Stability analysis of a dynamical model representing gene regulatory networks 

      Ahsen, M.E.; Özbay H.; Niculescu, S.I. (2012)
      In this paper we perform stability analysis of a class of cyclic biological processes involving time delayed feedback. More precisely, we analyze the genetic regulatory network having nonlinearities with negative Schwarzian ...
    • Threats and solutions for genomic data privacy 

      Ayday, E.; Hubaux, Jean-Pierre (Springer International Publishing, 2015)
      With the help of rapidly developing technology, DNA sequencing is becoming less expensive. As a consequence, the research in genomics has gained speed in paving the way to personalized (genomic) medicine, and geneticists ...