Browsing by Keywords "Fibrosis"
Now showing items 1-3 of 3
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Identification of the fibrogenic cells in the liver
(Bilkent University, 2022-03)The liver is an important multitasking organ with diverse functions to maintain body homeostasis. Adjustment of glucose level, detoxification, secretion of blood proteins, and synthesis of bile acids are the among these ... -
Increased SGK1 activity potentiates mineralocorticoid/NaCl-induced kidney injury
(American Physiological Society, 2021-04-08)Serum and glucocorticoid-regulated kinase 1 (SGK1) stimulates aldosterone-dependent renal Na reabsorption and modulates blood pressure. In addition, genetic ablation or pharmacological inhibition of SGK1 limits the development ... -
Therapeutic potential of an immunosuppressive oligodeoxynucleotide encapsulated within liposomes on bleomycin-induced mouse model of lung inflammation and fibrosis
(Bilkent University, 2019-05)Systemic sclerosis (SSc) is an autoimmune/autoinflammatory disease with unknown etiology. It is characterized by vascular dysfunction, inflammation and disseminated fibrosis of skin or internal organs. Although its prevalence ...
