Browsing by Keywords "Fast disintegrating"

Now showing items 1-3 of 3

Antibacterial nanofibers of pullulan/tetracycline-cyclodextrin inclusion complexes for fast-disintegrating oral drug delivery

Hsiung, E.; Celebioglu, A.; Chowdhury, R.; Kilic, M. E.; Durgun, Engin; Altier, C.; Uyar, T. (Elsevier Inc., 2021-12-08)

Tetracycline is a widely used antibiotic suffering from poor water solubility and low bioavailability. Here, hydroxypropyl-beta-cyclodextrin (HPβCD) was used to form inclusion complexes (IC) of tetracycline with 2:1 M ratio ...
Ondansetron/Cyclodextrin inclusion complex nanofibrous webs for potential orally fast-disintegrating antiemetic drug delivery

Hsiung, E.; Celebioglu, A.; Emin Kilic, M.; Durgun, Engin (Elsevier, 2022-07-25)

Ondansetron (ODS) is an effective antiemetic drug which suffers from limited solubility and bioavailability during oral administration due to first-pass metabolism. However, these limitations can be mitigated through ...
Orally fast disintegrating cyclodextrin/prednisolone inclusion-complex nanofibrous webs for potential steroid medications

Çelebioğlu, A.; Wang, N.; Kılıç, M. E.; Durgun, Engin; Uyar, T. (American Chemical Society, 2021-12-06)

Prednisolone is a widely used immunosuppressive and anti-inflammatory drug type that suffers from low aqueous solubility and bioavailability. Due to the inclusion complexation with cyclodextrins (CDs), prednisolone’s ...