Browsing by Keywords "Drug repurposing"
Now showing items 1-3 of 3
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Discovery of novel agents for liver cancer therapeutics and characterization of their bioactivities on cellular pathways
(Bilkent University, 2015-12)Hepatocellular carcinoma is the second deadliest and fifth most common cancer type worldwide. Due to the limited therapy options, it is crucial to develop novel targeted therapeutic agents that provide better prognosis ... -
Identification of preclinical implications for novel indole-benzimidazoles and phenothiazines using in vitro cancer cell line and in vivo zebrafish models
(Bilkent University, 2020-09)Breast cancer (BC) and hepatocellular carcinoma (HCC) are two major health problems with significant mortality rates. Although drug therapies are available, therapeutic success remains limited. Because of low bioavailability, ... -
Mineralocorticoid and glucocorticoid receptors as novel targets in breast and liver cancer therapies
(Bilkent University, 2021-01)Cell signaling is a complex phenomenon and is maintained through intertwined signal transmissions within and in-between the cells. Anti-cancer therapies are often challenged by this fact due to crosstalk-associated ...
