Now showing items 1-9 of 9

    • The antiproliferative effect of celecoxib loaded pNIPAM nanoparticles 

      Bayyurt, B.; Hasirci V. (2012)
      The aim of this study was to design a drug delivery system based on poly(N-isopropylacrylamide) (pNIPAM) nanoparticles (NPs). The model drug, Celecoxib, is a cyclooxygenase-2 inhibitor and has a great potential in ...
    • Biosystems engineering of prokaryotes with tumor-killing capacities 

      Kalyoncu, E.; Olmez, T. T.; Ozkan, A. D.; Sarioglu, O. F. (Bentham Science Publishers Ltd., 2016)
      Certain bacteria selectively attack tumor tissues and trigger tumor shrinkage by producing toxins and modulating the local immune system, but their clinical utility is limited because of the dangers posed by systemic ...
    • Drug delivery system based on cyclodextrin-naproxen inclusion complex incorporated in electrospun polycaprolactone nanofibers 

      Canbolat, M. F.; Celebioglu A.; Uyar T. (Elsevier, 2014)
      In this study, we select naproxen (NAP) as a reference drug and electrospun poly (e-caprolactone) (PCL) nanofibers as a fibrous matrix for our drug-delivery system. NAP was complexed with beta-cyclodextrin (βCD) to form ...
    • Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine 

      Fais, S.; O'Driscoll, L.; Borras, F. E.; Buzas, E.; Camussi, G.; Cappello, F.; Carvalho, J.; Cordeiro Da Silva, A.; Del Portillo, H.; El Andaloussi, S.; Ficko Trček, T.; Furlan, R.; Hendrix, A.; Gursel, I.; Kralj-Iglic, V.; Kaeffer, B.; Kosanovic, M.; Lekka, M. E.; Lipps, G.; Logozzi, M.; Marcilla, A.; Sammar, M.; Llorente, A.; Nazarenko, I.; Oliveira, C.; Pocsfalvi, G.; Rajendran, L.; Raposo, G.; Rohde, E.; Siljander, P.; Van, N. G.; Vasconcelos, M. H.; Yáñez-Mó, M.; Yliperttula, M. L.; Zarovni, N.; Zavec, A. B.; Giebel, B. (American Chemical Society, 2016-03)
      Recent research has demonstrated that all body fluids assessed contain substantial amounts of vesicles that range in size from 30 to 1000 nm and that are surrounded by phospholipid membranes containing different membrane ...
    • Gemcitabine integrated nano-prodrug carrier system 

      Hamsici, S.; Ekiz, M. S.; Ciftci, G. C.; Tekinay, A. B.; Guler, M. O. (American Chemical Society, 2017)
      Peptide nanomaterials have received a great deal of interest in drug-delivery applications due to their biodegradability, biocompatibility, suitability for large-scale synthesis, high drug-loading capacities, targeting ...
    • Injectable in situ forming microparticles: A novel drug delivery system 

      Yapar, E. A.; Inal, Ö.; Özkan, Y.; Baykara, T. (2012)
      Pharmaceutical formulation research has recently been focusing on delivery systems which provide long therapeutic effects and reduced side effects, and involving simplified production stages and facilitated application ...
    • Local delivery of doxorubicin through supramolecular peptide amphiphile nanofiber gels 

      Cinar, G.; Ozdemir, A.; Hamsici, S.; Gunay, G.; Dana, A.; Tekinay, A. B.; Guler, M. O. (Royal Society of Chemistry, 2017)
      Peptide amphiphiles (PAs) self-assemble into supramolecular nanofiber gels that provide a suitable environment for encapsulation of both hydrophobic and hydrophilic molecules. The PA gels have significant advantages for ...
    • Microfluidic device for synthesis of chitosan nanoparticles 

      Cetin, B.; Taze, S.; Asik, M.D.; Tuncel, S.A. (2013)
      Chitosan nanoparticles have a biodegradable, biocompatible, non-toxic structure, and commonly used for drug delivery systems. In this paper, simulation of a microfluidic device for the synthesis of chitosan nanoparticle ...
    • Non-covalent functionalized SWNTs as delivery agents for novel Bodipy-based potential PDT sensitizers 

      Erbas, S.; Gorgulu, A.; Kocakusakogullari, M.; Akkaya, E. U. (2009)
      Pyrenyl-functionalized distyryl-Bodipy sensitizer attached non-covalently to SWNTs was shown to generate singlet oxygen when excited at 660 nm with a red LED array; this work emphasizes the potential of SWNT as a viable ...