Browsing by Keywords "Dietary restriction"
Now showing items 1-6 of 6
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Age-related synapse loss in hippocampal CA3 is not reversed by caloric restriction
(Pergamon Press, 2010)Caloric restriction (CR) is a reduction of total caloric intake without a decrease in micronutrients or a disproportionate reduction of any one dietary component. While CR attenuates age-related cognitive deficits in tasks ... -
Caloric restriction eliminates the aging-related decline in NMDA and AMPA receptor subunits in the rat hippocampus and induces homeostasis
(ElsevierAysel Sabuncu Brain Research Center (BAM), 2007)Caloric restriction (CR) extends life span and ameliorates the aging-related decline in hippocampal-dependent cognitive function. In the present study, we compared subunit levels of NMDA and AMPA types of the glutamate ... -
Effects of aging and short-term dietary restriction on neurogenesis and cellular senescence in the zebrafish (Danio Reio) brain
(Bilkent University, 2016-09)Currently we know from rodent and fish studies that adult neuron generation is reduced but still continues in old animals with a dynamic change throughout aging. This process occurs mainly in hippocampal region, which is ... -
Short-term dietary restriction in old zebrafish changes cell senescence mechanisms
(Elsevier, 2016-10)Brain aging is marked by a decline in cognitive abilities and associated with neurodegenerative disorders. Recent studies have shown, neurogenesis continues into adulthood but is known to be decreasing during advancing age ... -
Short-term dietary restriction maintains synaptic plasticity whereas short-term overfeeding alters cellular dynamics in the aged brain: evidence from the zebrafish model organism
(Elsevier, 2021-06-19)Increased caloric intake (OF) impairs quality of life causing comorbidities with other diseases and cognitive deficits, whereas dietary restriction (DR) increases healthspan by preventing age-related deteriorations. To ... -
Zebrafish-A model organism for studying the neurobiological mechanisms underlying cognitive brain aging and use of potential interventions
(Frontiers Media S.A., 2018)Classically, the zebrafish model organism has been used to elucidate the genetic and cellular mechanisms related to development since the embryo forms and grows externally following fertilization. This provides insight ...
