Browsing by Keywords "DNA-PK"
Now showing items 1-4 of 4
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DNA damage-dependent interaction of the nuclear matrix protein C1D with translin-associated factor X (TRAX)
(2002)The nuclear matrix protein C1D is an activator of the DNA-dependent protein kinase (DNA-PK), which is essential for the repair of DNA double-strand breaks (DSBs) and V(D)J recombination. C1D is phosphorylated very efficiently ... -
DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D
(1998)DNA-dependent protein kinase (DNA-PK), which is involved in DNA double- strand break repair and V(D)J recombination, is comprised of a DNA-targeting component termed Ku and an ~465-kD catalytic subunit, DNA-PK(cs). Although ... -
Induction of apoptosis by overexpression of the DNA-binding and DNA-PK-activating protein C1D
(1999)Apoptosis is induced in various tumor cell lines by vector-dependent overexpression of the conserved gene C1D that encodes a DNA-binding and DNA-PK-activating protein. C1D is physiologically expressed in 50 human tissues ... -
Role of the nuclear matrix protein C1D in regulation of transcription
(Bilkent University, 2001)The nuclear matrix protein C1D is an activator of DNA-dependent protein kinase (DNAPK), which is involved in non-homologous end joining and V(D)J recombination. Moreover, the nuclear matrix proteins C1D was shown to be ...