Browsing by Keywords "DNA-PK"

DNA damage-dependent interaction of the nuclear matrix protein C1D with translin-associated factor X (TRAX)

Erdemir, T.; Bilican, B.; Oncel, D.; Goding, C. R.; Yavuzer, U. (2002)

The nuclear matrix protein C1D is an activator of the DNA-dependent protein kinase (DNA-PK), which is essential for the repair of DNA double-strand breaks (DSBs) and V(D)J recombination. C1D is phosphorylated very efficiently ...

DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D

Yavuzer, U.; Smith, G. C. M.; Bliss, T.; Werner, D.; Jackson, S. P. (1998)

DNA-dependent protein kinase (DNA-PK), which is involved in DNA double- strand break repair and V(D)J recombination, is comprised of a DNA-targeting component termed Ku and an ~465-kD catalytic subunit, DNA-PK(cs). Although ...

Induction of apoptosis by overexpression of the DNA-binding and DNA-PK-activating protein C1D

Rothbarth, K.; Spiess, E.; Juodka, B.; Yavuzer, U.; Nehls, P.; Stammer, H.; Werner, D. (1999)

Apoptosis is induced in various tumor cell lines by vector-dependent overexpression of the conserved gene C1D that encodes a DNA-binding and DNA-PK-activating protein. C1D is physiologically expressed in 50 human tissues ...

Role of the nuclear matrix protein C1D in regulation of transcription

Öncel, Dilhan (Bilkent University, 2001)

The nuclear matrix protein C1D is an activator of DNA-dependent protein kinase (DNAPK), which is involved in non-homologous end joining and V(D)J recombination. Moreover, the nuclear matrix proteins C1D was shown to be ...