Browsing by Keywords "Chemotherapy resistance"
Now showing items 1-5 of 5
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Epithelial-to-mesenchymal transition is not a major modulating factor in the cytotoxic response to natural products in cancer cell lines
(MDPI AG, 2021-09-27)Numerous natural products exhibit antiproliferative activity against cancer cells by modulating various biological pathways. In this study, we investigated the potential use of eight natural compounds (apigenin, curcumin, ... -
Identifying and targeting coding/non-coding molecular switches regulating drug resistance and metastasis in breast cancer
(Bilkent University, 2017-09)Breast cancer is the second most common cancer and the leading cause of cancer associated deaths in women worldwide. Despite the availability of large number and various types of therapy agents which are effective in ... -
miR-200c: a versatile watchdog in cancer progression, EMT, and drug resistance
(Springer Verlag, 2016-06)MicroRNAs (miRNAs) are 20–22-nucleotide small endogenous non-coding RNAs which regulate gene expression at post-transcriptional level. In the last two decades, identification of almost 2600 miRNAs in human and their potential ... -
Multiomics approaches to overcome drug resistance in cancer
(Bilkent University, 2021-09)Chemotherapy resistance remains one of the major challenges in cancer treatment. Most of the studies on drug resistance have focused on genetic evolution of cancer cells; however, this focus has shifted to non-genetic and ... -
Targeting mirna-protein regulatory networks to enhance chemotherapy response in BRCA1-mutated TNBCs
(Bilkent University, 2016-09)Breast cancer is the second most common cancer and the leading cause of cancer associated deaths in women worldwide. Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. BRCA1-mutated TNBC ...
