Browsing by Keywords "Cell Death"

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Synthesis and anticancer activity evaluation of some benzothiazole-piperazine derivatives

Gurdal, E.E.; Buclulgan, E.; Durmaz I.; Cetin-Atalay, R.; Yarim, M. (Bentham Science Publishers B.V., 2015)

Synthesis, characterization and cytotoxic activities of ten benzothiazole-piperazine derivatives were reported. In vitro cytotoxic activities of compounds were screened against hepatocellular (HUH-7), breast (MCF-7) and ...
Synthesis of novel substituted purine derivatives and identification of the cell death mechanism

Demir, Z.; Guven, E.B.; Ozbey, S.; Kazak, C.; Atalay, R.C.; Tuncbilek, M. (Elsevier Masson SAS, 2015)

Novel substituted adenine and purine derivatives were designed and synthesized.Compound 36 displayed the greatest cytotoxic activity with IC50 less than 1 1/4M.36 induces senescence associated cell death, which was ...