Browsing by Keywords "Cartilage"

Characterization of peptide amphiphile nanofibers their interactions with chondroprogenitor cells and morphological analysis of tissues from transgenic animals

Tombuloğlu, Ayşegül (Bilkent University, 2012)

Peptide amphiphiles, molecules able to self assemble into three dimensional networks resembling to extracellular matrix which is excessive in cartilage tissue, are suitable candidates for overcoming cartilage tissue ...

Chondrogenic differentiation of mesenchymal stem cells on glycosaminoglycan-mimetic peptide nanofibers

Yaylaci, S .U.; Sen, M.; Bulut, O.; Arslan, E.; Güler, Mustafa O.; Tekinay, A. B. (American Chemical Society, 2016)

Glycosaminoglycans (GAGs) are important extracellular matrix components of cartilage tissue and provide biological signals to stem cells and chondrocytes for development and functional regeneration of cartilage. Among their ...

Effect of double growth factor release on cartilage tissue engineering

Ertan, A.B.; Yilgor P.; Bayyurt, B.; Çalikoǧlu, A.C.; Kaspar Ç.; Kök F.N.; Kose G.T.; Hasirci V. (2013)

The effects of double release of insulin-like growth factor I (IGF-I) and growth factor β1 (TGF-β1) from nanoparticles on the growth of bone marrow mesenchymal stem cells and their differentiation into cartilage cells were ...

Materials for articular cartilage regeneration

Tombuloglu, Ayşegül; Tekinay, Ayşe B.; Güler, Mustafa O. (Bentham Science Publishers B.V., 2012)

Many health problems remaining to be untreatable throughout the human history can be overcome by utilizing new biomedical materials. Healing cartilage defects is one of the problems causing significant health issue due to ...

Peptide-based materials for cartilage tissue regeneration

Hastar, Nurcan; Arslan, Elif.; Güler, Mustafa O.; Tekinay, Ayse B. (Springer New York LLC, 2017)

Cartilaginous tissue requires structural and metabolic support after traumatic or chronic injuries because of its limited capacity for regeneration. However, current techniques for cartilage regeneration are either invasive ...

Supramolecular GAG-like self-assembled glycopeptide nanofibers Induce chondrogenesis and cartilage regeneration

Yaylaci, U. S.; Ekiz, M. S.; Arslan, E.; Can, N.; Kilic, E.; Ozkan, H.; Orujalipoor, I.; Ide, S.; Tekinay, A. B.; Güler, Mustafa O. (American Chemical Society, 2016)

Glycosaminoglycans (GAGs) and glycoproteins are vital components of the extracellular matrix, directing cell proliferation, differentiation, and migration and tissue homeostasis. Here, we demonstrate supramolecular GAG-like ...