Now showing items 1-6 of 6

    • The impact of psychosis genome-wide associated ZNF804A variation on verbal fluency connectivity 

      Tecelão, D.; Mendes, A.; Martins, D.; Bramon, E.; Toulopoulou, T.; Kravariti, E.; Murray, R.; Prata, D. (Elsevier, 2018-03)
      Schizophrenia (SCZ) and bipolar disorder (BD) have high heritability. Genome-wide association studies (GWAS) have identified ZNF804A as a significant risk gene for both illnesses. A validation of this finding at the brain ...
    • Investigation of Heschl's gyrus and planum temporale in patients with schizophrenia and bipolar disorder: a proton magnetic resonance spectroscopy study 

      Atagün, M. İ.; Şıkoğlu, E. M.; Can, S. S.; Karakaş-Uğurlu, G.; Ulusoy-Kaymak, S.; Çayköylü, A.; Algın, O.; Phillips, M. L.; Moore, C. M.; Öngür, D. (Elsevier, 2015)
      Background: Superior temporal cortices include brain regions dedicated to auditory processing and several lines of evidence suggest structural and functional abnormalities in both schizophrenia and bipolar disorder within ...
    • Neurochemical differences between bipolar disorder type I and II in superior temporal cortices: a proton magnetic resonance spectroscopy study 

      Atagün, M. İ.; Şıkoğlu, E. M.; Can, S. S.; Uğurlu, G. K.; Kaymak, S. U.; Çayköylü, A.; Algın, O.; Phillips, M. L.; Moore, C. M.; Öngür, D. (Elsevier B.V., 2018)
      Background: Despite the diagnostic challenges in categorizing bipolar disorder subtypes, bipolar I and II disorders (BD-I and BD-II respectively) are valid indices for researchers. Subtle neurobiological differences may ...
    • Perisylvian GABA levels in schizophrenia and bipolar disorder 

      Atagün, M. İ.; Şıkoglu, M. E.; Soykan, Ç.; Can, S. S.; Ulusoy-Kaymak S.; Çayköylü, A.; Algın O.; Phillips, M. L.; Öngür, D.; Moore, C. M. (Elsevier Ireland Ltd, 2017)
      The aim of this study is to measure GABA levels of perisylvian cortices in schizophrenia and bipolar disorder patients, using proton magnetic resonance spectroscopy (1H-MRS). Patients with schizophrenia (n = 25), bipolar ...
    • A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains 

      Ranlund, S.; Calafato, S.; Thygesen, J. H.; Lin, K.; Cahn, W.; Crespo-Facorro, B.; Díez, A.; Forti, M. D.; Iyegbe, C.; Jablensky, A.; Jones, R.; Hall, M.; Kahn, R.; Kalaydjieva, L.; Kravariti, E.; McDonald, C.; McIntosh, A. M.; McQuillin, A.; Picchioni, M.; Prata, D. P.; Rujescu, D.; Schulze, K.; Shaikh, M.; Toulopoulou, T.; Haren, N.; Zwarte, S. M. C.; Os, J.; Vassos, E.; Walshe, M.; Lewis, C.; Murray, R. M.; Powell, J.; Bramon, E. (John Wiley & Sons, Inc., 2018)
      This large multi‐center study investigates the relationships between genetic risk for schizophrenia and bipolar disorder, and multi‐modal endophenotypes for psychosis. The sample included 4,242 individuals; 1,087 patients ...
    • Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders 

      Calafato, M. S.; Thygesen, J. H.; Ranlund, S.; Zartaloudi, E.; Cahn, W.; Crespo-Facorro, B.; Díez-Revuelta, A.; Forti, M. D.; Hall, M. -H.; Iyegbe, C.; Jablensky, A.; Kahn, R.; Kalaydjieva, L.; Kravariti, E.; Lin, K.; McDonald, C.; McIntosh, A. M.; McQuillin, A.; Picchioni, M.; Rujescu, D.; Shaikh, M.; Toulopoulou, T.; Os, J. V.; Vassos, E.; Walshe, M.; Powell, J.; Lewis, C. M.; Murray, R. M.; Bramon, E. (2018)
      Background There is increasing evidence for shared genetic susceptibility between schizophrenia and bipolar disorder. Although genetic variants only convey subtle increases in risk individually, their combination into a ...