Now showing items 1-7 of 7

    • The Association between familial risk and brain abnormalities Is disease specific: an ENIGMA-relatives study of schizophrenia and bipolar disorder 

      Zwarte, S. M. C.; Brouwer, R. M.; Agartz, I.; Alda, M.; Aleman, A.; Alpert, K. I.; Bearden, C. E.; Bertolino, A.; Bois, C.; Bonvino, A.; Bramon, E.; Buimer, E.; Cahn, W.; Cannon, D. M.; Cannon, T. D.; Caseras, X.; Castro-Fornieles, J.; Chen, Q.; Serna, E.; Giorgio, A. D.; Doucet, G.; Eker, M. C.; Erk, S.; Fears, S.; Foley, S.; Frangou, S.; Frankland, A.; Fullerton, J.; Glahn, D.; Goghari, V.; Goldman, A.; Gonul, A.; Gruber, O.; Haan, L.; Hajek, T.; Hawkins, E.; Heinz, A.; Hillegers, M.; Pol, H.; Hultman, C.; Ingvar, M.; Johansson, V.; Jönsson, E.; Kane, K.; Kempton, M.; Koenis, M.; Kopecek, M.; Krabbendam, L.; Krämer, B.; Lawrie, S.; Lenroot, R.; Marcelis, M.; Marsman, J-B; Mattay, V.; McDonald, C.; Meyer-Lindenberg, A.; Michielse, S.; Mitchell, P.; Moreno, D.; Murray, R.; Mwangi, B.; Najt, P.; Neilson, E.; Newport, J.; Os, J.; Overs, B.; Ozerdem, A.; Picchioni, M.; Richter, A.; Roberts, G.; Aydogan, A. S.; Schofield, P.; Simsek, F.; Soares, J.; Sugranyes, G.; Toulopoulou, Timothea; Tronchin, G.; Walter, H.; Wang, L.; Weinberger, D.; Whalley, H.; Yalin, N.; Andreassen, O.; Ching, C.; Erp, T.; Turner, J.; Jahanshad, N.; Thompson, P.; Kahn, R.; Haren, N. (Elsevier, 2019)
      Abstract Background Schizophrenia and bipolar disorder share genetic liability, and some structural brain abnormalities are common to both conditions. First-degree relatives of patients with schizophrenia (FDRs-SZ) show ...
    • The impact of psychosis genome-wide associated ZNF804A variation on verbal fluency connectivity 

      Tecelão, D.; Mendes, A.; Martins, D.; Bramon, E.; Toulopoulou, T.; Kravariti, E.; Murray, R.; Prata, D. (Elsevier, 2018-03)
      Schizophrenia (SCZ) and bipolar disorder (BD) have high heritability. Genome-wide association studies (GWAS) have identified ZNF804A as a significant risk gene for both illnesses. A validation of this finding at the brain ...
    • Investigation of Heschl's gyrus and planum temporale in patients with schizophrenia and bipolar disorder: a proton magnetic resonance spectroscopy study 

      Atagün, M. İ.; Şıkoğlu, E. M.; Can, S. S.; Karakaş-Uğurlu, G.; Ulusoy-Kaymak, S.; Çayköylü, A.; Algın, O.; Phillips, M. L.; Moore, C. M.; Öngür, D. (Elsevier, 2015)
      Background: Superior temporal cortices include brain regions dedicated to auditory processing and several lines of evidence suggest structural and functional abnormalities in both schizophrenia and bipolar disorder within ...
    • Neurochemical differences between bipolar disorder type I and II in superior temporal cortices: a proton magnetic resonance spectroscopy study 

      Atagün, M. İ.; Şıkoğlu, E. M.; Can, S. S.; Uğurlu, G. K.; Kaymak, S. U.; Çayköylü, A.; Algın, O.; Phillips, M. L.; Moore, C. M.; Öngür, D. (Elsevier B.V., 2018)
      Background: Despite the diagnostic challenges in categorizing bipolar disorder subtypes, bipolar I and II disorders (BD-I and BD-II respectively) are valid indices for researchers. Subtle neurobiological differences may ...
    • Perisylvian GABA levels in schizophrenia and bipolar disorder 

      Atagün, M. İ.; Şıkoglu, M. E.; Soykan, Ç.; Can, S. S.; Ulusoy-Kaymak S.; Çayköylü, A.; Algın O.; Phillips, M. L.; Öngür, D.; Moore, C. M. (Elsevier Ireland Ltd, 2017)
      The aim of this study is to measure GABA levels of perisylvian cortices in schizophrenia and bipolar disorder patients, using proton magnetic resonance spectroscopy (1H-MRS). Patients with schizophrenia (n = 25), bipolar ...
    • A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains 

      Ranlund, S.; Calafato, S.; Thygesen, J. H.; Lin, K.; Cahn, W.; Crespo-Facorro, B.; Díez, A.; Forti, M. D.; Iyegbe, C.; Jablensky, A.; Jones, R.; Hall, M.; Kahn, R.; Kalaydjieva, L.; Kravariti, E.; McDonald, C.; McIntosh, A. M.; McQuillin, A.; Picchioni, M.; Prata, D. P.; Rujescu, D.; Schulze, K.; Shaikh, M.; Toulopoulou, T.; Haren, N.; Zwarte, S. M. C.; Os, J.; Vassos, E.; Walshe, M.; Lewis, C.; Murray, R. M.; Powell, J.; Bramon, E. (John Wiley & Sons, Inc., 2018)
      This large multi‐center study investigates the relationships between genetic risk for schizophrenia and bipolar disorder, and multi‐modal endophenotypes for psychosis. The sample included 4,242 individuals; 1,087 patients ...
    • Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders 

      Calafato, M. S.; Thygesen, J. H.; Ranlund, S.; Zartaloudi, E.; Cahn, W.; Crespo-Facorro, B.; Díez-Revuelta, A.; Forti, M. D.; Hall, M. -H.; Iyegbe, C.; Jablensky, A.; Kahn, R.; Kalaydjieva, L.; Kravariti, E.; Lin, K.; McDonald, C.; McIntosh, A. M.; McQuillin, A.; Picchioni, M.; Rujescu, D.; Shaikh, M.; Toulopoulou, T.; Os, J. V.; Vassos, E.; Walshe, M.; Powell, J.; Lewis, C. M.; Murray, R. M.; Bramon, E. (2018)
      Background There is increasing evidence for shared genetic susceptibility between schizophrenia and bipolar disorder. Although genetic variants only convey subtle increases in risk individually, their combination into a ...