Browsing by Keywords "Biomineralization"
Now showing items 1-11 of 11
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Bioactive peptide nanofibers for bone tissue regeneration
(Bilkent University, 2017-06)Replacement and repair of bone tissue that is lost due to fractures, tumor resection, degenerative diseases and infections still remain major clinical challenges. Autografting, allografting and xenografting are the current ... -
Biomineralization of calcium phosphate crystals controlled by protein-protein interactions
(American Chemical Society, 2019)Hydroxyapatite (HAP) is the major biomineral of bone. Despite the large number of studies addressing HAP formation, a fundamental understanding of the critical roles of HAP-forming proteins in vitro is needed. Effects of ... -
Biomineralization with engineered cellular systems
(Bilkent University, 2019-08)Hydroxyapatite (HAP) is the final product of bone biomineralization process and HAP formation is controlled by proteins, enzymes and small molecules secreted to extracellular matrix (ECM). Among these molecules, alkaline ... -
A comprehensive methodology for determining the most informative mammographic features
(2013)This study aims to determine the most informative mammographic features for breast cancer diagnosis using mutual information (MI) analysis. Our Health Insurance Portability and Accountability Act-approved database consists ... -
Dentin phosphoprotein mimetic peptide nanofibers promote biomineralization
(WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim, 2019)Dentin phosphoprotein (DPP) is a major component of the dentin matrix playing crucial role in hydroxyapatite deposition during bone mineralization, making it a prime candidate for the design of novel materials for bone and ... -
Design, synthesis and characterization of bioinspired nanomaterials for engineering and biomedicine
(Bilkent University, 2014)Nature is an inspirational school for materials scientists. Natural selection process puts a massive pressure on biological organisms giving rise to effective strategies for fabricating materials, which generally outperform ... -
Genetically programmed engineered cells for biomaterials synthesis
(Bilkent University, 2021-01)Several organisms can process nanomaterials and producing in various sizes and morphologies in mild conditions by utilizing specific proteins. In sea sponges, silicatein proteins play a key role in synthesizing silica ... -
A glycosaminoglycan mimetic peptide nanofiber gel as an osteoinductive scaffold
(Royal Society of Chemistry, 2016)Biomineralization of the extracellular matrix (ECM) plays a crucial role in bone formation. Functional and structural biomimetic native bone ECM components can therefore be used to change the fate of stem cells and induce ... -
Mineralized peptide nanofiber gels for enhanced osteogenic differentiation
(Wiley, 2018)Mineral deposition is observed in both bacterial and eukaryotic organisms through a broad range of mechanisms. Both organic and inorganic components play crucial roles in the formation of mineralized tissues, and acidic ... -
One-dimensional peptide nanostructure templated growth of iron phosphate nanostructures for lithium-ion battery cathodes
(American Chemical Society, 2016-06)Template-directed synthesis of nanomaterials can provide benefits such as small crystalline size, high surface area, large surface-to-volume ratio, and structural stability. These properties are important for shorter ... -
Self-assembled template-directed synthesis of one-dimensional silica and titania nanostructures
(2011)Mineralized biological materials such as shells, skeleton, and teeth experience biomineralization. Biomimetic materials exploit the biomineralization process to form functional organic-inorganic hybrid nanostructures. In ...